BACKGROUND AND AIMS: The knee is one of the most commonly affected joints in haemophilic arthropathy leading to stiffness and disability. It is the aim of this study to investigate the outcome of corrective osteotomies around the knee. PATIENTS AND METHODS: We report on the long-term results of ten osteotomies around the knee for severe haemophilic arthropathy and axial deviation at an average of 7.25+/-1.8 years postoperatively. Seven high tibial (preoperatively 7.2+/-2 degrees varus) and three supracondylar osteotomies (preoperatively 7+/-3 degrees valgus) were performed on seven patients (three of them bilateral). RESULTS: The clinical score of the Advisory Board of the World Federation of Haemophilia (average 7.4 points preoperatively) remained unchanged in two patients, improved in three patients and deteriorated in five patients. The radiological Pettersson score (average 8.2 points preoperatively) showed a worsening of 2.5 points over the time. Patients reported a subjective improvement for seven osteotomies, with sports activity in three patients, although the range of motion did not change significantly. Total knee arthroplasty was considered to be a failure, i.e. endpoint of follow-up. Six knees were replaced in four patients by total arthroplasty after a mean of 6.6 years. CONCLUSION: Although survival of osteotomies around the knee in haemophilic arthropathy is lower than in non-haemophilic patients, we think that it is a choice of treatment, which, at least, postpones the indication for total knee arthroplasty in this young patient group.
BACKGROUND AND AIMS: The knee is one of the most commonly affected joints in haemophilic arthropathy leading to stiffness and disability. It is the aim of this study to investigate the outcome of corrective osteotomies around the knee. PATIENTS AND METHODS: We report on the long-term results of ten osteotomies around the knee for severe haemophilic arthropathy and axial deviation at an average of 7.25+/-1.8 years postoperatively. Seven high tibial (preoperatively 7.2+/-2 degrees varus) and three supracondylar osteotomies (preoperatively 7+/-3 degrees valgus) were performed on seven patients (three of them bilateral). RESULTS: The clinical score of the Advisory Board of the World Federation of Haemophilia (average 7.4 points preoperatively) remained unchanged in two patients, improved in three patients and deteriorated in five patients. The radiological Pettersson score (average 8.2 points preoperatively) showed a worsening of 2.5 points over the time. Patients reported a subjective improvement for seven osteotomies, with sports activity in three patients, although the range of motion did not change significantly. Total knee arthroplasty was considered to be a failure, i.e. endpoint of follow-up. Six knees were replaced in four patients by total arthroplasty after a mean of 6.6 years. CONCLUSION: Although survival of osteotomies around the knee in haemophilic arthropathy is lower than in non-haemophilic patients, we think that it is a choice of treatment, which, at least, postpones the indication for total knee arthroplasty in this young patient group.
Authors: Oana Viola Badulescu; Paul Dan Sirbu; Carmen Ungureanu; Alin Pȋnzariu; Elena Cojocaru; Nina Filip; Iris Bararu-Bojan; Maria Vladeanu; Manuela Ciocoiu Journal: Exp Ther Med Date: 2021-07-14 Impact factor: 2.447