Literature DB >> 14617726

Mood changes with deep brain stimulation of STN and GPi: results of a pilot study.

M S Okun1, J Green, R Saben, R Gross, K D Foote, J L Vitek.   

Abstract

The results of this study suggest that there are mood changes associated with deep brain stimulation of the subthalamic nucleus (STN) and the globus pallidus interna (GPi). Further, optimal placement of electrodes in both STN and GPi seems to result in overall improvement in mood and is associated with a lower incidence of adverse mood effects than stimulation outside the optimal site. Preliminary data from this study, however, suggest that slight movement dorsal or ventral to the site of optimal motor performance may be associated with more adverse changes in mood with STN stimulation than with GPi stimulation.

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Year:  2003        PMID: 14617726      PMCID: PMC1738229          DOI: 10.1136/jnnp.74.11.1584

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  29 in total

Review 1.  Parkinson's disease therapeutics: new developments and challenges since the introduction of levodopa.

Authors:  Yoland Smith; Thomas Wichmann; Stewart A Factor; Mahlon R DeLong
Journal:  Neuropsychopharmacology       Date:  2011-09-28       Impact factor: 7.853

2.  Deep brain stimulation in Parkinson's disease.

Authors:  S J Groiss; L Wojtecki; M Südmeyer; A Schnitzler
Journal:  Ther Adv Neurol Disord       Date:  2009-11       Impact factor: 6.570

3.  Influence of bilateral Stn-stimulation on psychiatric symptoms and psychosocial functioning in patients with Parkinson's disease.

Authors:  K Kalteis; H Standhardt; I Kryspin-Exner; T Brücke; D Volc; F Alesch
Journal:  J Neural Transm (Vienna)       Date:  2005-12-16       Impact factor: 3.575

4.  High frequency stimulation of the subthalamic nucleus modulates neurotransmission in limbic brain regions of the rat.

Authors:  Christine Winter; Christoph Lemke; Reinhard Sohr; Wassilios Meissner; Daniel Harnack; Georg Juckel; Rudolf Morgenstern; Andreas Kupsch
Journal:  Exp Brain Res       Date:  2007-10-26       Impact factor: 1.972

Review 5.  Limbic, associative, and motor territories within the targets for deep brain stimulation: potential clinical implications.

Authors:  Atchar Sudhyadhom; Frank J Bova; Kelly D Foote; Christian A Rosado; Lindsey Kirsch-Darrow; Michael S Okun
Journal:  Curr Neurol Neurosci Rep       Date:  2007-07       Impact factor: 5.081

6.  Long-term neuropsychiatric outcomes after pallidal stimulation in primary and secondary dystonia.

Authors:  Sara Meoni; Mateusz Zurowski; Andres M Lozano; Mojgan Hodaie; Yu-Yan Poon; Melanie Fallis; Valerie Voon; Elena Moro
Journal:  Neurology       Date:  2015-07-08       Impact factor: 9.910

Review 7.  Deep brain stimulation (DBS) at the interface of neurology and psychiatry.

Authors:  Nolan R Williams; Michael S Okun
Journal:  J Clin Invest       Date:  2013-11-01       Impact factor: 14.808

8.  DBS candidates that fall short on a levodopa challenge test: alternative and important indications.

Authors:  Takashi Morishita; Maryam Rahman; Kelly D Foote; Kyle M Fargen; Charles E Jacobson; Hubert H Fernandez; Ramon L Rodriguez; Irene A Malaty; Dawn Bowers; Christopher J Hass; Yoichi Katayama; Takamitsu Yamamoto; Michael S Okun
Journal:  Neurologist       Date:  2011-09       Impact factor: 1.398

Review 9.  Deep Brain Stimulation Emergencies: How the New Technologies Could Modify the Current Scenario.

Authors:  Giovanni Cossu; Mariachiara Sensi
Journal:  Curr Neurol Neurosci Rep       Date:  2017-07       Impact factor: 5.081

10.  STN vs. GPi Deep Brain Stimulation: Translating the Rematch into Clinical Practice.

Authors:  Nolan R Williams; Kelly D Foote; Michael S Okun
Journal:  Mov Disord Clin Pract       Date:  2014-04-01
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