Literature DB >> 1461659

The amino acid sequence of a mammalian MAP kinase kinase.

A Ashworth1, S Nakielny, P Cohen, C Marshall.   

Abstract

The amino acid sequence of the dual specificity mitogen-activated protein kinase kinase (MAPKK) has been determined by cDNA cloning and amino acid sequencing. MAPKK (393 residues, Mr 43,330) is a new member of the protein kinase subclass that comprises byr1 and STE7 that are involved in pheromone dependent signal transduction in yeast, wis1 a mitotic regulator in S. pombe and PBS2, which confers antibiotic resistance in S. cerevisiae.

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Year:  1992        PMID： 1461659

Source DB:  PubMed          Journal:  Oncogene        ISSN： 0950-9232            Impact factor:   9.867


  21 in total

1.  Metabolic labeling of mitogen-activated protein kinase kinase in A431 cells demonstrates phosphorylation on serine and threonine residues.

Authors:  N G Ahn; J S Campbell; R Seger; A L Jensen; L M Graves; E G Krebs
Journal:  Proc Natl Acad Sci U S A       Date:  1993-06-01       Impact factor: 11.205

Review 2.  Cell-signaling targets for antitumour drug development.

Authors:  V G Brunton; P Workman
Journal:  Cancer Chemother Pharmacol       Date:  1993       Impact factor: 3.333

3.  Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

Authors:  G Pagès; P Lenormand; G L'Allemain; J C Chambard; S Meloche; J Pouysségur
Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-15       Impact factor: 11.205

4.  Activation of the mitogen-activated protein kinase pathway in Triton X-100 disrupted NIH-3T3 cells by p21 ras and in vitro by plasma membranes from NIH 3T3 cells.

Authors:  P Dent; J Wu; G Romero; L A Vincent; D Castle; T W Sturgill
Journal:  Mol Biol Cell       Date:  1993-05       Impact factor: 4.138

Review 5.  Networking with mitogen-activated protein kinases.

Authors:  S L Pelech; D L Charest; G P Mordret; Y L Siow; C Palaty; D Campbell; L Charlton; M Samiei; J S Sanghera
Journal:  Mol Cell Biochem       Date:  1993-11       Impact factor: 3.396

6.  RAS and RAF-1 form a signalling complex with MEK-1 but not MEK-2.

Authors:  T Jelinek; A D Catling; C W Reuter; S A Moodie; A Wolfman; M J Weber
Journal:  Mol Cell Biol       Date:  1994-12       Impact factor: 4.272

7.  Molecular cloning, expression, and characterization of the human mitogen-activated protein kinase p44erk1.

Authors:  D L Charest; G Mordret; K W Harder; F Jirik; S L Pelech
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

8.  Protein kinase A antagonizes platelet-derived growth factor-induced signaling by mitogen-activated protein kinase in human arterial smooth muscle cells.

Authors:  L M Graves; K E Bornfeldt; E W Raines; B C Potts; S G Macdonald; R Ross; E G Krebs
Journal:  Proc Natl Acad Sci U S A       Date:  1993-11-01       Impact factor: 11.205

9.  Identification and characterization of a new mammalian mitogen-activated protein kinase kinase, MKK2.

Authors:  J Wu; J K Harrison; P Dent; K R Lynch; M J Weber; T W Sturgill
Journal:  Mol Cell Biol       Date:  1993-08       Impact factor: 4.272

10.  Dual phosphorylation and autophosphorylation in mitogen-activated protein (MAP) kinase activation.

Authors:  J H Her; S Lakhani; K Zu; J Vila; P Dent; T W Sturgill; M J Weber
Journal:  Biochem J       Date:  1993-11-15       Impact factor: 3.857
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