Literature DB >> 14616368

Efficacy of pulsed dye laser treatment of port wine stain malformations of the lower limb.

S Sommer1, D C Seukeran, R A Sheehan-Dare.   

Abstract

BACKGROUND: There is relatively little information about treatment of port wine stains (PWS) of the lower limb. Few studies have specifically addressed the efficacy of pulsed dye laser (PDL) treatment of a PWS on the lower limb and there is no information on the relative efficacy at different sites on the lower limb. It has been suggested that treatment is not as successful when compared with the face and postinflammatory hyperpigmentation has been reported to be a significant problem.
OBJECTIVES: To review retrospectively patients who attended for PDL treatment of PWS affecting the lower limb and assess the efficacy and adverse effects with particular reference to skin site.
METHODS: A retrospective review was carried out of patients attending the Leeds Dermatology Laser Centre for treatment of a PWS on the lower limb with a 585-nm PDL.
RESULTS: A total of 52 sites in 39 patients were treated: 17 on the thigh, 31 on the lower leg and four on the foot. The mean number of sessions per patient was 14, with an excellent outcome in seven treatment sites (13.5%), good in 13 (25%), moderate in 21 (40.4%) and poor outcome in 11 (21.1%). Patients were generally pleased with their results with a mean improvement of 7 on a scale of 0-10. Perifollicular persistence of the PWS was observed in six sites (11.5%). Adverse effects occurred in 36 patients (92.3%), most commonly hyperpigmentation (87%). Six patients (15.4%) developed atrophic scarring and four (10.3%) hypopigmentation. Atrophie blanche-like changes were seen in four patients on the lower leg. Hypertrophic scarring was not seen.
CONCLUSIONS: Although physician-assessed good or excellent responses of 38.5% are lower than frequently reported for other skin sites and adverse effects may be more frequent, patient satisfaction with treatment was generally high. Patients with PWS on the lower limb merit a trial of PDL treatment.

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Year:  2003        PMID: 14616368     DOI: 10.1046/j.1365-2133.2003.05467.x

Source DB:  PubMed          Journal:  Br J Dermatol        ISSN: 0007-0963            Impact factor:   9.302


  10 in total

1.  Current concepts: laser treatment of adult vascular lesions.

Authors:  Tomi L Wall
Journal:  Semin Plast Surg       Date:  2007-08       Impact factor: 2.314

Review 2.  Laser and IPL treatment of port-wine stains: therapy options, limitations, and practical aspects.

Authors:  Annette Klein; Wolfgang Bäumler; Michael Landthaler; Philipp Babilas
Journal:  Lasers Med Sci       Date:  2011-03-10       Impact factor: 3.161

3.  [Potential and limitations of dye laser therapy for capillary malformations].

Authors:  A Klein; U Hohenleutner
Journal:  HNO       Date:  2014-01       Impact factor: 1.284

4.  Does interval time between pulsed dye laser treatments for port-wine stains influence outcome? A systematic review and meta-analysis.

Authors:  Igor Snast; Moshe Lapidoth; Ran Kaftory; Adi Nosrati; Emmilia Hodak; Daniel Mimouni; Efrat Solomon-Cohen; Assi Levi
Journal:  Lasers Med Sci       Date:  2021-02-13       Impact factor: 3.161

5.  Can we predict the outcome of 595-nm wavelength pulsed dye laser therapy on capillary vascular malformations from the first beginning: a pilot study of efficacy co-related factors in 686 Chinese patients.

Authors:  Xiangxia Liu; Yanfang Fan; Jiexin Huang; Ruixi Zeng; Guangling Cao; Mukai Chen; Wenna Chen; Jinming Tang
Journal:  Lasers Med Sci       Date:  2014-12-07       Impact factor: 3.161

6.  Adverse effects reported in pulsed dye laser treatment for port wine stains.

Authors:  Wendy J Wareham; Richard P Cole; Sue L Royston; Philip A Wright
Journal:  Lasers Med Sci       Date:  2008-04-17       Impact factor: 3.161

7.  Japanese clinical practice guidelines for vascular anomalies 2017.

Authors:  Hidefumi Mimura; Sadanori Akita; Akihiro Fujino; Masatoshi Jinnin; Mine Ozaki; Keigo Osuga; Hiroki Nakaoka; Eiichi Morii; Akira Kuramochi; Yoko Aoki; Yasunori Arai; Noriko Aramaki; Masanori Inoue; Yuki Iwashina; Tadashi Iwanaka; Shigeru Ueno; Akihiro Umezawa; Michio Ozeki; Junko Ochi; Yoshiaki Kinoshita; Masakazu Kurita; Shien Seike; Nobuyuki Takakura; Masataka Takahashi; Takao Tachibana; Kumiko Chuman; Shuji Nagata; Mitsunaga Narushima; Yasunari Niimi; Shunsuke Nosaka; Taiki Nozaki; Kazuki Hashimoto; Ayato Hayashi; Satoshi Hirakawa; Atsuko Fujikawa; Yumiko Hori; Kentaro Matsuoka; Hideki Mori; Yuki Yamamoto; Shunsuke Yuzuriha; Naoaki Rikihisa; Shoji Watanabe; Shinichi Watanabe; Tatsuo Kuroda; Shunsuke Sugawara; Kosuke Ishikawa; Satoru Sasaki
Journal:  Jpn J Radiol       Date:  2020-04       Impact factor: 2.374

8.  Japanese Clinical Practice Guidelines for Vascular Anomalies 2017.

Authors:  Hidefumi Mimura; Sadanori Akita; Akihiro Fujino; Masatoshi Jinnin; Mine Ozaki; Keigo Osuga; Hiroki Nakaoka; Eiichi Morii; Akira Kuramochi; Yoko Aoki; Yasunori Arai; Noriko Aramaki; Masanori Inoue; Yuki Iwashina; Tadashi Iwanaka; Shigeru Ueno; Akihiro Umezawa; Michio Ozeki; Junko Ochi; Yoshiaki Kinoshita; Masakazu Kurita; Shien Seike; Nobuyuki Takakura; Masataka Takahashi; Takao Tachibana; Kumiko Chuman; Shuji Nagata; Mitsunaga Narushima; Yasunari Niimi; Shunsuke Nosaka; Taiki Nozaki; Kazuki Hashimoto; Ayato Hayashi; Satoshi Hirakawa; Atsuko Fujikawa; Yumiko Hori; Kentaro Matsuoka; Hideki Mori; Yuki Yamamoto; Shunsuke Yuzuriha; Naoaki Rikihisa; Shoji Watanabe; Shinichi Watanabe; Tatsuo Kuroda; Shunsuke Sugawara; Kosuke Ishikawa; Satoru Sasaki
Journal:  J Dermatol       Date:  2020-03-22       Impact factor: 4.005

9.  Treatment of port wine stains with pulsed dye laser: a retrospective study of 848 cases in Shandong Province, People's Republic of China.

Authors:  Wenhao Shi; Jinliang Wang; Yan Lin; Jianhui Geng; Haixia Wang; Yueqin Gong; Huaxu Liu; Furen Zhang
Journal:  Drug Des Devel Ther       Date:  2014-12-12       Impact factor: 4.162

Review 10.  Site-specific pharmaco-laser therapy: A novel treatment modality for refractory port wine stains.

Authors:  M Ingmar van Raath; Jojanneke E van Amesfoort; Martin Hermann; Yasin Ince; Maurice J Zwart; Agustina V Echague; Yan Chen; Baoyue Ding; Xuan Huang; Gert Storm; Michal Heger
Journal:  J Clin Transl Res       Date:  2019-05-01
  10 in total

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