| Literature DB >> 14615113 |
B Mosimaneotsile1, E A Talbot, T L Moeti, N M Hone, G Moalosi, H J Moffat, E J Lee, T A Kenyon.
Abstract
To exclude tuberculosis, WHO/UNAIDS recommends considering medical history, symptom screen, and chest radiograph before starting tuberculosis prevention in people infected with HIV. The value of a chest radiograph for this purpose is unknown. We prospectively assessed 935 HIV-infected outpatients seeking isoniazid preventive therapy. Of 935 patients, 692 (74%) had no signs or symptoms of tuberculosis. Of these 692, 123 (18%) were lost during the chest radiograph process, and one (0.2%) of the remaining 563 was diagnosed with tuberculosis on the basis of the chest radiograph. A screening chest radiograph should not be required routinely for asymptomatic people taking isoniazid as preventive treatment in settings able to screen for signs and symptoms of tuberculosis.Entities:
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Year: 2003 PMID： 14615113 DOI： 10.1016/s0140-6736(03)14745-9
Source DB: PubMed Journal: Lancet ISSN： 0140-6736 Impact factor: 79.321