Literature DB >> 14614653

Does polymorphism C1377T of the calcitonin receptor gene determine bone mineral density in postmenopausal women?

I Zofková1, K Zajícková, M Hill, A Krepelová.   

Abstract

In a cross-sectional study we investigated the potential association between CALCR polymorphism (C1377T) and bone mineral density in 114 postmenopausal women. T homozygotes had higher BMD (g/cm2) at the femoral neck compared with carriers of C allele (p < 0.02, ANCOVA). Means of BMD at the lumbar spine did not differ among the genotypes (ANCOVA). In conclusion, the CALCR gene is associated with bone mass at the femoral neck in postmenopausal women.

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Year:  2003        PMID： 14614653     DOI： 10.1055/s-2003-44293

Source DB:  PubMed          Journal:  Exp Clin Endocrinol Diabetes        ISSN： 0947-7349            Impact factor:   2.949


  6 in total

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Authors:  H-J Lee; S-Y Kim; G S Kim; J-Y Hwang; Y-J Kim; B Jeong; T-H Kim; E K Park; S H Lee; H-L Kim; J-M Koh; J-Y Lee
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3.  Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fractures.

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4.  Genetic analysis of vertebral trabecular bone density and cross-sectional area in older men.

Authors:  J M Zmuda; L M Yerges-Armstrong; S P Moffett; L Klei; C M Kammerer; K Roeder; J A Cauley; A Kuipers; K E Ensrud; C S Nestlerode; A R Hoffman; C E Lewis; T F Lang; E Barrett-Connor; R E Ferrell; E S Orwoll
Journal:  Osteoporos Int       Date:  2010-12-09       Impact factor: 4.507

Review 5.  The role of GPCRs in bone diseases and dysfunctions.

Authors:  Jian Luo; Peng Sun; Stefan Siwko; Mingyao Liu; Jianru Xiao
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  6 in total

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