BACKGROUND: There are reports on favourable course and outcome of schizophrenia in lowincome countries. The aim of the present study was to examine onset and clinical course of the illness in a community-based sample in rural Ethiopia based on crosssectional information. METHOD: A two-stage survey was carried out in Butajira-Ethiopia, a predominantly rural district. Altogether 68,378 individuals aged 15-49 years were CIDI-interviewed, of whom 2,159 were identified as cases according to the CIDI interview with regard to psychotic or affective disorders. Key informants identified another group of 719 individuals as being probable cases and a total of 2,285 individuals were SCAN-interviewed. The present paper reports on cases with schizophrenia. RESULTS: There were 321 cases of schizophrenia giving an estimated lifetime prevalence of 4.7/1,000). Of the cases,83.2% (N = 267) were males. Mean age of first onset of psychotic symptoms for males was 23.8 (sd 8.6) compared to 21.0 (sd 7.8) for females (P = 0.037; 95 %CI 0.16-5.47). Over 80% had negative symptoms and over 67% reported continuous course of the illness. Less than 10% had a history of previous treatment with neuroleptic medication. About 7% were vagrants, 9 % had a history of assaultive behaviour,and 3.8% had attempted suicide. The male to female ratio was nearly 5:1. CONCLUSION: This large community-based study differs from most previous studies in terms of higher male to female ratio, earlier age of onset in females and the predominance of negative symptoms.
BACKGROUND: There are reports on favourable course and outcome of schizophrenia in lowincome countries. The aim of the present study was to examine onset and clinical course of the illness in a community-based sample in rural Ethiopia based on crosssectional information. METHOD: A two-stage survey was carried out in Butajira-Ethiopia, a predominantly rural district. Altogether 68,378 individuals aged 15-49 years were CIDI-interviewed, of whom 2,159 were identified as cases according to the CIDI interview with regard to psychotic or affective disorders. Key informants identified another group of 719 individuals as being probable cases and a total of 2,285 individuals were SCAN-interviewed. The present paper reports on cases with schizophrenia. RESULTS: There were 321 cases of schizophrenia giving an estimated lifetime prevalence of 4.7/1,000). Of the cases,83.2% (N = 267) were males. Mean age of first onset of psychotic symptoms for males was 23.8 (sd 8.6) compared to 21.0 (sd 7.8) for females (P = 0.037; 95 %CI 0.16-5.47). Over 80% had negative symptoms and over 67% reported continuous course of the illness. Less than 10% had a history of previous treatment with neuroleptic medication. About 7% were vagrants, 9 % had a history of assaultive behaviour,and 3.8% had attempted suicide. The male to female ratio was nearly 5:1. CONCLUSION: This large community-based study differs from most previous studies in terms of higher male to female ratio, earlier age of onset in females and the predominance of negative symptoms.
Authors: Vikram Patel; Mario Maj; Alan J Flisher; Mary J De Silva; Mirja Koschorke; Martin Prince Journal: World Psychiatry Date: 2010-10 Impact factor: 49.548
Authors: Daniel Mamah; Anne Mbwayo; Victoria Mutiso; Deanna M Barch; John N Constantino; Thelma Nsofor; Lincoln Khasakhala; David M Ndetei Journal: Compr Psychiatry Date: 2011-09-25 Impact factor: 3.735
Authors: Senait Ghebrehiwet; Tithi Baul; Juliana L Restivo; Teshome Shibre Kelkile; Anne Stevenson; Bizu Gelaye; Abebaw Fekadu; Maji Hailemariam; Eshetu Girma; Solomon Teferra; Victoria Canelos; David C Henderson; Christina P C Borba Journal: Glob Public Health Date: 2019-10-20
Authors: Wing Chung Chang; Corine Sau Man Wong; Eric Yu Hai Chen; Linda Chiu Wa Lam; Wai Chi Chan; Roger Man Kin Ng; Se Fong Hung; Eric Fuk Chi Cheung; Pak Chung Sham; Helen Fung Kum Chiu; Ming Lam; Edwin Ho Ming Lee; Tin Po Chiang; Lap Kei Chan; Gary Kar Wai Lau; Allen Ting Chun Lee; Grace Tak Yu Leung; Joey Shuk Yan Leung; Joseph Tak Fai Lau; Jim van Os; Glyn Lewis; Paul Bebbington Journal: Schizophr Bull Date: 2017-10-21 Impact factor: 9.306