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Literature DB >> 14614319

HOX genes: emerging stars in cancer.

Hexin Chen¹, Saraswati Sukumar.

Abstract

Entities: Disease

Mesh：

Year: 2003 PMID： 14614319 DOI： 10.4161/cbt.2.5.525

Source DB: PubMed Journal: Cancer Biol Ther ISSN： 1538-4047 Impact factor: 4.742

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Cited

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25 in total

1. Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.

Authors: Imran Hussain; Arunoday Bhan; Khairul I Ansari; Paromita Deb; Samara A M Bobzean; Linda I Perrotti; Subhrangsu S Mandal
Journal: Biochim Biophys Acta Date: 2015-02-25

2. HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

Authors: Khairul I Ansari; Imran Hussain; Bishakha Shrestha; Sahba Kasiri; Subhrangsu S Mandal
Journal: J Mol Biol Date: 2011-06-12 Impact factor: 5.469

3. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

Authors: Penney M Gilbert; Janna K Mouw; Meredith A Unger; Johnathon N Lakins; Mawuse K Gbegnon; Virginia B Clemmer; Miriam Benezra; Jonathan D Licht; Nancy J Boudreau; Kelvin K C Tsai; Alana L Welm; Michael D Feldman; Barbara L Weber; Valerie M Weaver
Journal: J Clin Invest Date: 2010-04-12 Impact factor: 14.808

4. Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression.

Authors: Khairul I Ansari; Bishakha Shrestha; Imran Hussain; Sahba Kasiri; Subhrangsu S Mandal
Journal: Biochemistry Date: 2011-04-05 Impact factor: 3.162

5. The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences.

Authors: Yun Chen; Alejandro D Leal; Sejal Patel; David H Gorski
Journal: J Biol Chem Date: 2006-10-30 Impact factor: 5.157

6. Antisense oligonucleotide mediated knockdown of HOXC13 affects cell growth and induces apoptosis in tumor cells and over expression of HOXC13 induces 3D-colony formation.

Authors: Sahba Kasiri; Khairul I Ansari; Imran Hussain; Arunoday Bhan; Subhrangsu S Mandal
Journal: RSC Adv Date: 2012-12-18 Impact factor: 3.361

HOX genes: emerging stars in cancer.

1. Bisphenol-A induces expression of HOXC6, an estrogen-regulated homeobox-containing gene associated with breast cancer.

2. HOXC6 Is transcriptionally regulated via coordination of MLL histone methylase and estrogen receptor in an estrogen environment.

3. HOXA9 regulates BRCA1 expression to modulate human breast tumor phenotype.

4. Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression.

5. The homeobox gene GAX activates p21WAF1/CIP1 expression in vascular endothelial cells through direct interaction with upstream AT-rich sequences.

6. Antisense oligonucleotide mediated knockdown of HOXC13 affects cell growth and induces apoptosis in tumor cells and over expression of HOXC13 induces 3D-colony formation.

7. Silencing of HOXB9 suppresses cellular proliferation, angiogenesis, migration and invasion of prostate cancer cells.

8. BP1 Homeoprotein Enhances Metastatic Potential in ER-negative Breast Cancer.

9. Functional characterization of the HOXB13 promoter region.

10. Methylation of homeobox genes is a frequent and early epigenetic event in breast cancer.