BACKGROUND: The aim of this study was to evaluate the microstructure of the EEG sleep of depressed subjects by cyclic alternating pattern (CAP) analysis. METHODS: 78 patients affected by major depression and 18 control subjects matched for age and sex underwent a full night polysomnographic study. RESULTS: A significant increase in CAP rate (60 versus 35%) was found in the patients group compared to controls while no significant difference was found with the traditional analysis. CONCLUSION: In depressed subjects CAP analysis is able to show a microstructural sleep impairment, which is not evident at the macrostructural level, providing an objective measure of sleep disturbance in those patients.
BACKGROUND: The aim of this study was to evaluate the microstructure of the EEG sleep of depressed subjects by cyclic alternating pattern (CAP) analysis. METHODS: 78 patients affected by major depression and 18 control subjects matched for age and sex underwent a full night polysomnographic study. RESULTS: A significant increase in CAP rate (60 versus 35%) was found in the patients group compared to controls while no significant difference was found with the traditional analysis. CONCLUSION: In depressed subjects CAP analysis is able to show a microstructural sleep impairment, which is not evident at the macrostructural level, providing an objective measure of sleep disturbance in those patients.
Authors: Albert C Yang; Cheng-Hung Yang; Chen-Jee Hong; Shih-Jen Tsai; Chung-Hsun Kuo; Chung-Kang Peng; Joseph E Mietus; Ary L Goldberger; Robert J Thomas Journal: Psychophysiology Date: 2011-02 Impact factor: 4.016
Authors: G Della Marca; B Farina; G F Mennuni; S Mazza; M Di Giannantonio; V Spadini; S De Risio; A Ciocca; M Mazza Journal: Eat Weight Disord Date: 2004-03 Impact factor: 4.652
Authors: Gloria Y Yeh; Joseph E Mietus; Chung-Kang Peng; Russell S Phillips; Roger B Davis; Peter M Wayne; Ary L Goldberger; Robert J Thomas Journal: Sleep Med Date: 2007-08-03 Impact factor: 3.492