| Literature DB >> 14612172 |
C Monrigal1, P Beurrier, F-J Mercier, C Boyer-Neumann, P Gillard.
Abstract
Glanzmann's thrombasthenia is a thrombopathy due to a qualitative or quantitative abnormality of glycoproteins GP IIb-IIIa. Pregnancy is uncommon and dangerous. Delivery often results in important haemorrhage, which is treated with HLA compatible platelet and packed red blood cells transfusions. Platelet transfusion may produce antibody that render transfusions ineffective. Newborn thrombocytopenia is occasionally severe, but is always transitory. Caesarean section has no proven advantage. We report a case with caesarean, which was successfully managed by platelet transfusion over seven peripartum days, with no adverse event. Literature is discussed.Entities:
Mesh:
Year: 2003 PMID: 14612172 DOI: 10.1016/s0750-7658(03)00319-8
Source DB: PubMed Journal: Ann Fr Anesth Reanim ISSN: 0750-7658