Literature DB >> 14612172

[Glanzmann's thrombasthenia and pregnancy: a case and review of the literature].

C Monrigal1, P Beurrier, F-J Mercier, C Boyer-Neumann, P Gillard.   

Abstract

Glanzmann's thrombasthenia is a thrombopathy due to a qualitative or quantitative abnormality of glycoproteins GP IIb-IIIa. Pregnancy is uncommon and dangerous. Delivery often results in important haemorrhage, which is treated with HLA compatible platelet and packed red blood cells transfusions. Platelet transfusion may produce antibody that render transfusions ineffective. Newborn thrombocytopenia is occasionally severe, but is always transitory. Caesarean section has no proven advantage. We report a case with caesarean, which was successfully managed by platelet transfusion over seven peripartum days, with no adverse event. Literature is discussed.

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Year:  2003        PMID: 14612172     DOI: 10.1016/s0750-7658(03)00319-8

Source DB:  PubMed          Journal:  Ann Fr Anesth Reanim        ISSN: 0750-7658


  1 in total

Review 1.  [Glanzmann's thrombasthenia and pregnancy: report of a case and literature review].

Authors:  Myriam Rachad; Hikmat Chaara; Fatim zahra Fdili; Sofia Jayi; Hakimat Bouguern; Moulay Abdelilah Melhouf
Journal:  Pan Afr Med J       Date:  2011-12-21
  1 in total

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