Literature DB >> 14611839

Synthesis and antimycobacterial activity of capuramycin analogues. Part 2: acylated derivatives of capuramycin-related compounds.

Hitoshi Hotoda1, Makiko Daigo, Miyuki Furukawa, Kazuhiro Murayama, Chikako Akiyama Hasegawa, Masakatsu Kaneko, Yasunori Muramatsu, Michiko Miyazawa Ishii, Shun-ichi Miyakoshi, Toshio Takatsu, Masatoshi Inukai, Masayo Kakuta, Tomomi Abe, Takashi Fukuoka, Yukio Utsui, Satoshi Ohya.   

Abstract

Acylated derivatives of capuramycin and A-500359A were synthesized and tested for antimycobacterial activity. Compound 20 having a decanoyl group showed very potent activity.

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Year:  2003        PMID： 14611839     DOI： 10.1016/s0960-894x(03)00597-3

Source DB:  PubMed          Journal:  Bioorg Med Chem Lett        ISSN： 0960-894X            Impact factor:   2.823


  12 in total

1.  Chemical modification of capuramycins to enhance antibacterial activity.

Authors:  Elena Bogatcheva; Tia Dubuisson; Marina Protopopova; Leo Einck; Carol A Nacy; Venkata M Reddy
Journal:  J Antimicrob Chemother       Date:  2010-12-23       Impact factor: 5.790

Review 2.  A comprehensive review of glycosylated bacterial natural products.

Authors:  Sherif I Elshahawi; Khaled A Shaaban; Madan K Kharel; Jon S Thorson
Journal:  Chem Soc Rev       Date:  2015-11-07       Impact factor: 54.564

3.  A biocatalytic approach to capuramycin analogues by exploiting a substrate permissive N-transacylase CapW.

Authors:  Xiaodong Liu; Yuanyuan Jin; Wenlong Cai; Keith D Green; Anwesha Goswami; Sylvie Garneau-Tsodikova; Koichi Nonaka; Satoshi Baba; Masanori Funabashi; Zhaoyong Yang; Steven G Van Lanen
Journal:  Org Biomol Chem       Date:  2016-04-06       Impact factor: 3.876

4.  The Biosynthesis of Capuramycin-type Antibiotics: IDENTIFICATION OF THE A-102395 BIOSYNTHETIC GENE CLUSTER, MECHANISM OF SELF-RESISTANCE, AND FORMATION OF URIDINE-5'-CARBOXAMIDE.

Authors:  Wenlong Cai; Anwesha Goswami; Zhaoyong Yang; Xiaodong Liu; Keith D Green; Sandra Barnard-Britson; Satoshi Baba; Masanori Funabashi; Koichi Nonaka; Manjula Sunkara; Andrew J Morris; Anatol P Spork; Christian Ducho; Sylvie Garneau-Tsodikova; Jon S Thorson; Steven G Van Lanen
Journal:  J Biol Chem       Date:  2015-04-08       Impact factor: 5.157

5.  Identification of the biosynthetic gene cluster for the pacidamycin group of peptidyl nucleoside antibiotics.

Authors:  Wenjun Zhang; Bohdan Ostash; Christopher T Walsh
Journal:  Proc Natl Acad Sci U S A       Date:  2010-09-08       Impact factor: 11.205

6.  In vitro antimicrobial activities of capuramycin analogues against non-tuberculous mycobacteria.

Authors:  Tia Dubuisson; Elena Bogatcheva; Manju Y Krishnan; Michael T Collins; Leo Einck; Carol A Nacy; Venkata M Reddy
Journal:  J Antimicrob Chemother       Date:  2010-10-14       Impact factor: 5.790

7.  Highly efficient O-glycosylations with p-tolyl thioribosides and p-TolSOTf.

Authors:  Michio Kurosu; Kai Li
Journal:  J Org Chem       Date:  2008-12-19       Impact factor: 4.354

Review 8.  Structures of Bacterial MraY and Human GPT Provide Insights into Rational Antibiotic Design.

Authors:  Ellene H Mashalidis; Seok-Yong Lee
Journal:  J Mol Biol       Date:  2020-03-19       Impact factor: 5.469

9.  Therapeutic efficacy of SQ641-NE against Mycobacterium tuberculosis.

Authors:  Boris Nikonenko; Venkata M Reddy; Elena Bogatcheva; Marina Protopopova; Leo Einck; Carol A Nacy
Journal:  Antimicrob Agents Chemother       Date:  2013-10-21       Impact factor: 5.191

Review 10.  Mechanism of action of nucleoside antibacterial natural product antibiotics.

Authors:  Timothy D H Bugg; Rachel V Kerr
Journal:  J Antibiot (Tokyo)       Date:  2019-08-30       Impact factor: 2.649
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