Literature DB >> 14611154

Viridepyronone, a new antifungal 6-substituted 2H-pyran-2-one produced by Trichoderma viride.

Antonio Evidente1, Annalisa Cabras, Lucia Maddau, Salvatorica Serra, Anna Andolfi, Andrea Motta.   

Abstract

A new antifungal 6-substituted 2H-pyran-2-one, named viridepyronone, has been isolated from a cultural filtrate of a strain of Trichoderma viride showing antagonistic activity in vitro toward Sclerotium rolfsii, which is the causal agent of crown and stem rot of artichoke. Viridepyronone was characterized as 6-(4-oxopentyl)-2H-pyran-2-one 2 with spectroscopic methods. Bioassays showed that viridepyronone had a good antifungal activity against S. rolfsii, and its minimum inhibitory concentration (over 90% inhibition) was found to be 196 microg/mL. This is the first report of viridepyronone produced by any species of fungi.

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Year:  2003        PMID: 14611154     DOI: 10.1021/jf034708j

Source DB:  PubMed          Journal:  J Agric Food Chem        ISSN: 0021-8561            Impact factor:   5.279


  7 in total

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  7 in total

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