OBJECTIVE: The authors compared the subjective functioning of 137 middle-aged and elderly outpatients with schizophrenia or schizoaffective disorder with that of 77 normal subjects, using the Medical Outcomes Study (MOS) 36-Item Short Form (SF-36) Health Survey. The SF-36 is a generic outcome measure that provides a profile of functioning in several different domains. METHODS: Measures included the MOS-SF-36, along with standardized instruments for assessing psychopathology, cognition, dyskinesia, quality of well-being, and everyday functioning. RESULTS: Schizophrenia patients reported greater disability than normal subjects in all areas (mental and physical) assessed by the SF-36 except for bodily pain. Logistic-regression analysis suggested that the best predictors for being in the schizophrenia group were 1) physical and emotional functioning and 2) pain. Among patients, age at onset of illness, depressive symptoms, and cognitive functioning predicted 39% of the variance in the SF-36 Mental Health Composite score. CONCLUSIONS: Subjective functioning of older people with schizophrenia is affected by perceived physical health, depressive symptoms, and cognitive impairment.
OBJECTIVE: The authors compared the subjective functioning of 137 middle-aged and elderly outpatients with schizophrenia or schizoaffective disorder with that of 77 normal subjects, using the Medical Outcomes Study (MOS) 36-Item Short Form (SF-36) Health Survey. The SF-36 is a generic outcome measure that provides a profile of functioning in several different domains. METHODS: Measures included the MOS-SF-36, along with standardized instruments for assessing psychopathology, cognition, dyskinesia, quality of well-being, and everyday functioning. RESULTS:Schizophreniapatients reported greater disability than normal subjects in all areas (mental and physical) assessed by the SF-36 except for bodily pain. Logistic-regression analysis suggested that the best predictors for being in the schizophrenia group were 1) physical and emotional functioning and 2) pain. Among patients, age at onset of illness, depressive symptoms, and cognitive functioning predicted 39% of the variance in the SF-36 Mental Health Composite score. CONCLUSIONS: Subjective functioning of older people with schizophrenia is affected by perceived physical health, depressive symptoms, and cognitive impairment.
Authors: Sally Shepherd; Colin A Depp; Gloria Harris; Maureen Halpain; Lawrence A Palinkas; Dilip V Jeste Journal: Schizophr Bull Date: 2010-07-05 Impact factor: 9.306
Authors: Jenille M Narvaez; Elizabeth W Twamley; Christine L McKibbin; Robert K Heaton; Thomas L Patterson Journal: Schizophr Res Date: 2007-10-04 Impact factor: 4.939
Authors: David P Folsom; Colin Depp; Barton W Palmer; Brent T Mausbach; Shahrokh Golshan; Ian Fellows; Veronica Cardenas; Thomas L Patterson; Helena C Kraemer; Dilip V Jeste Journal: Schizophr Res Date: 2009-01-24 Impact factor: 4.939
Authors: Maria Ginieri-Coccossis; Eugenia Triantafillou; Vlasis Tomaras; Ioannis A Liappas; George N Christodoulou; George N Papadimitriou Journal: Ann Gen Psychiatry Date: 2009-10-13 Impact factor: 3.455