Literature DB >> 14608432

Cool-Water Immersion and High-Voltage Electric Stimulation Curb Edema Formation in Rats.

Michael G. Dolan1, Anna M. Mychaskiw, Frank C. Mendel.   

Abstract

OBJECTIVE: Although cryotherapy and high-voltage electric stimulation, both alone and in combination, are commonly applied to curb acute edema, little evidence from randomized controlled studies supports these procedures. Our purpose was to examine the effects of cool-water immersion (CWI) at 12.8 degrees C (55 degrees F), cathodal high-voltage pulsed current (CHVPC) at 120 pulses per second and 90% of visible motor threshold, and the combination of CWI and CHVPC (CWI + CHVPC) on edema formation after impact injury to the hind limbs of rats. DESIGN AND
SETTING: Both feet of 34 rats were traumatized after hind-limb volumes were determined. Animals were randomly assigned to 1 of 3 groups: CWI (n = 10), CHVPC (n = 10), or CWI + CHVPC (n = 14). One randomly selected hind limb of each rat was exposed to four 30-minute treatments, interspersed with four 30-minute rest periods beginning immediately after posttraumatic limb volumes were determined. Contralateral limbs served as controls. Limbs remained dependent during all treatments, rest periods, and volumetric measurements.
SUBJECTS: We used 34 anesthetized Zucker Lean rats in this study. MEASUREMENTS: We measured limb volumes immediately before and after trauma and after each of 4 treatment and rest periods.
RESULTS: Volumes of treated limbs of all 3 experimental groups were smaller (P <.05) than those of untreated limbs. No treatment was more effective than another.
CONCLUSIONS: Cool-water immersion, cathodal high-voltage electric stimulation, and simultaneous application of these treatments were effective in curbing edema after blunt injury. Combining CWI and CHVPC was not more effective than either CWI or CHVPC alone.

Entities:  

Year:  2003        PMID: 14608432      PMCID: PMC233176     

Source DB:  PubMed          Journal:  J Athl Train        ISSN: 1062-6050            Impact factor:   2.860


  27 in total

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Journal:  J Orthop Sports Phys Ther       Date:  1993-05       Impact factor: 4.751

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Journal:  Clin Orthop Relat Res       Date:  1980 Jul-Aug       Impact factor: 4.176

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  6 in total

Review 1.  National Athletic Trainers' Association position statement: conservative management and prevention of ankle sprains in athletes.

Authors:  Thomas W Kaminski; Jay Hertel; Ned Amendola; Carrie L Docherty; Michael G Dolan; J Ty Hopkins; Eric Nussbaum; Wendy Poppy; Doug Richie
Journal:  J Athl Train       Date:  2013 Jul-Aug       Impact factor: 2.860

2.  Effects of Ibuprofen and High-Voltage Electric Stimulation on Acute Edema Formation After Blunt Trauma to Limbs of Rats.

Authors:  Michael G Dolan; Paul Graves; Chika Nakazawa; Teresa Delano; Alan Hutson; Frank C Mendel
Journal:  J Athl Train       Date:  2005-06       Impact factor: 2.860

3.  Effects of Cool-Water Immersion and High-Voltage Electric Stimulation for 3 Continuous Hours on Acute Edema in Rats.

Authors:  Michael G. Dolan; Anna M. Mychaskiw; Carl G. Mattacola; Frank C. Mendel
Journal:  J Athl Train       Date:  2003-12       Impact factor: 2.860

4.  Effect of high-voltage electrical stimulation on the albumin and histamine serum concentrations, edema, and pain in acute joint inflammation of rats.

Authors:  Maria C Sandoval; Carolina R Ramirez; Diana M Camargo; Thiago L Russo; Tania F Salvini
Journal:  Braz J Phys Ther       Date:  2015-04-27       Impact factor: 3.377

5.  Insulin treatment reverses the increase in atrogin-1 expression in atrophied skeletal muscles of diabetic rats with acute joint inflammation.

Authors:  Clara Maria Pinheiro-Dardis; Vânia Ortega Gutierres; Renata Pires Assis; Sabrina Messa Peviani; Gabriel Borges Delfino; João Luiz Quagliotti Durigan; Tania de Fátima Salvini; Amanda Martins Baviera; Iguatemy Lourenço Brunetti
Journal:  Ther Clin Risk Manag       Date:  2018-02-14       Impact factor: 2.423

6.  Effects of high voltage pulsed current stimulation with a visible contraction intensity on expression of TGF-β1 and synthesis of type I collagen in wound-induced white rats.

Authors:  Jae-Keun Jeon; Seung-Kyu Park; Joon-Hee Lee
Journal:  J Phys Ther Sci       Date:  2015-05-26
  6 in total

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