OBJECTIVES: To analyze the clinical features of uncinate process carcinoma of the pancreas and to improve the resection rate. METHODS: From January 1990 to June 1999, 10 patients with pancreas uncinate process carcinoma received Whipple's operation. Portal vein (PV) resection and reanastomosis were performed in 5 patients, and the resected length varied from 2.0 to 4.2 cm. Two patients underwent PV lateral wall partial resection. RESULTS: Among the 7 patients undergoing PV resection, 1 died of hepatic failure 3 days after operation. One patient suffered from postoperative chylous ascites. These 6 patients survived 13 to 29 months postoperatively. Among the 3 patients without PV resection, 2 survived 13 months and 14 months respectively. One patient was alive by the end of follow-up for 11.5 months postoperatively. CONCLUSION: Although uncinate process carcinoma of the pancreas has a tendency to invade the adjacent PV and superior mesentery vein, it should not be simply regarded as a contraindication of radical resection.
OBJECTIVES: To analyze the clinical features of uncinate process carcinoma of the pancreas and to improve the resection rate. METHODS: From January 1990 to June 1999, 10 patients with pancreas uncinate process carcinoma received Whipple's operation. Portal vein (PV) resection and reanastomosis were performed in 5 patients, and the resected length varied from 2.0 to 4.2 cm. Two patients underwent PV lateral wall partial resection. RESULTS: Among the 7 patients undergoing PV resection, 1 died of hepatic failure 3 days after operation. One patient suffered from postoperative chylous ascites. These 6 patients survived 13 to 29 months postoperatively. Among the 3 patients without PV resection, 2 survived 13 months and 14 months respectively. One patient was alive by the end of follow-up for 11.5 months postoperatively. CONCLUSION: Although uncinate process carcinoma of the pancreas has a tendency to invade the adjacent PV and superior mesentery vein, it should not be simply regarded as a contraindication of radical resection.
Authors: Lia Assumpcao; John L Cameron; Christopher L Wolfgang; Barish Edil; Michael A Choti; Joseph M Herman; Jean-Francois Geschwind; Kelvin Hong; Christos Georgiades; Richard D Schulick; Timothy M Pawlik Journal: J Gastrointest Surg Date: 2008-08-07 Impact factor: 3.452