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Literature DB >> 14605508

Neuroleptic malignant syndrome in juvenile neuronal ceroid lipofuscinosis associated with low-dose risperidone therapy.

L Vercammen¹, G M Buyse, J E F Proost, J L K Van Hove.

Abstract

We present a patient with juvenile neuronal ceroid lipofuscinosis who developed a neuroleptic malignant syndrome when treated for hallucinations with a very low dose of risperidone, an atypical neuroleptic medication with usually few extrapyramidal side-effects. The loss of dopaminergic neurons in this condition may make these patients more vulnerable to this severe adverse effect.

Entities: Chemical Disease Species

Mesh：

Substances：

Year: 2003 PMID： 14605508 DOI： 10.1023/a:1025916518457

Source DB: PubMed Journal: J Inherit Metab Dis ISSN： 0141-8955 Impact factor: 4.982

4 in total

Review 1. Neurology of the neuronal ceroid-lipofuscinoses: late infantile and juvenile types.

Authors: R M Boustany
Journal: Am J Med Genet Date: 1992-02-15

2. Spectrum of mutations in the Batten disease gene, CLN3.

Authors: P B Munroe; H M Mitchison; A M O'Rawe; J W Anderson; R M Boustany; T J Lerner; P E Taschner; N de Vos; M H Breuning; R M Gardiner; S E Mole
Journal: Am J Hum Genet Date: 1997-08 Impact factor: 11.025

3. Decreased striatal dopamine transporter density in JNCL patients with parkinsonian symptoms.

Authors: L Aberg; K Liewendahl; P Nikkinen; T Autti; J O Rinne; P Santavuori
Journal: Neurology Date: 2000-03-14 Impact factor: 9.910

Review 4. Pathogenesis of brain dysfunction in Batten disease.

Authors: S U Walkley; P A March; C E Schroeder; S Wurzelmann; R D Jolly
Journal: Am J Med Genet Date: 1995-06-05

4 in total

3 in total

Neuroleptic malignant syndrome in juvenile neuronal ceroid lipofuscinosis associated with low-dose risperidone therapy.

Review 1. Neurology of the neuronal ceroid-lipofuscinoses: late infantile and juvenile types.

2. Spectrum of mutations in the Batten disease gene, CLN3.

3. Decreased striatal dopamine transporter density in JNCL patients with parkinsonian symptoms.

Review 4. Pathogenesis of brain dysfunction in Batten disease.

Review 1. The neuropsychiatry of inborn errors of metabolism.

Review 2. Neuroleptic malignant syndrome associated with atypical antipsychotic drugs.

Review 3. Nosology and Phenomenology of Psychosis in Movement Disorders.