STUDY OBJECTIVES: To measure the accuracy and reliability of a portable home oximetry monitor with an automated analysis for the diagnosis of obstructive sleep apnea (OSA) in children. DESIGN: Prospective cohort study. SETTING: Alberta Lung Association Sleep Center, Alberta Children's Hospital Sleep Clinic. STUDY SUBJECTS: Consecutive, otherwise healthy children, aged 4 to 18 years, presenting to the Pediatric Sleep Service at the Alberta Children's Hospital for assessment of possible OSA. INTERVENTIONS: All subjects underwent 2 nights of monitoring in the home with an oximetry-based portable monitor with an automatic internal scoring algorithm. A third night of monitoring was done simultaneously with computerized laboratory polysomnography according to American Thoracic Society guidelines. MEASUREMENTS AND RESULTS: Both test-retest reliability of the portable monitor-based desaturation index (DI) between 2 nights at home and between laboratory and home were high using the Bland and Altman analysis (mean agreement, 0.32 and 0.64; limits of agreement, - 8.00 to 8.64 and - 0.75 to 6.50, respectively). The polysomnographic apnea-hypopnea index (AHI) agreed poorly with the portable monitor DI (mean difference, 1.27; limits of agreement, - 12.02 to 15.02). The sensitivity and specificity of the monitor for the identification of moderate sleep apnea (polysomnography AHI > 5/h) were 67% and 60%, respectively. CONCLUSION: Portable monitoring based only on oximetry alone is not adequate for the identification of OSA in otherwise healthy children.
STUDY OBJECTIVES: To measure the accuracy and reliability of a portable home oximetry monitor with an automated analysis for the diagnosis of obstructive sleep apnea (OSA) in children. DESIGN: Prospective cohort study. SETTING: Alberta Lung Association Sleep Center, Alberta Children's Hospital Sleep Clinic. STUDY SUBJECTS: Consecutive, otherwise healthy children, aged 4 to 18 years, presenting to the Pediatric Sleep Service at the Alberta Children's Hospital for assessment of possible OSA. INTERVENTIONS: All subjects underwent 2 nights of monitoring in the home with an oximetry-based portable monitor with an automatic internal scoring algorithm. A third night of monitoring was done simultaneously with computerized laboratory polysomnography according to American Thoracic Society guidelines. MEASUREMENTS AND RESULTS: Both test-retest reliability of the portable monitor-based desaturation index (DI) between 2 nights at home and between laboratory and home were high using the Bland and Altman analysis (mean agreement, 0.32 and 0.64; limits of agreement, - 8.00 to 8.64 and - 0.75 to 6.50, respectively). The polysomnographic apnea-hypopnea index (AHI) agreed poorly with the portable monitor DI (mean difference, 1.27; limits of agreement, - 12.02 to 15.02). The sensitivity and specificity of the monitor for the identification of moderate sleep apnea (polysomnography AHI > 5/h) were 67% and 60%, respectively. CONCLUSION: Portable monitoring based only on oximetry alone is not adequate for the identification of OSA in otherwise healthy children.
Authors: Roberto Hornero; Leila Kheirandish-Gozal; Gonzalo C Gutiérrez-Tobal; Mona F Philby; María Luz Alonso-Álvarez; Daniel Álvarez; Ehab A Dayyat; Zhifei Xu; Yu-Shu Huang; Maximiliano Tamae Kakazu; Albert M Li; Annelies Van Eyck; Pablo E Brockmann; Zarmina Ehsan; Narong Simakajornboon; Athanasios G Kaditis; Fernando Vaquerizo-Villar; Andrea Crespo Sedano; Oscar Sans Capdevila; Magnus von Lukowicz; Joaquín Terán-Santos; Félix Del Campo; Christian F Poets; Rosario Ferreira; Katalina Bertran; Yamei Zhang; John Schuen; Stijn Verhulst; David Gozal Journal: Am J Respir Crit Care Med Date: 2017-12-15 Impact factor: 21.405
Authors: Kristie R Ross; Amy Storfer-Isser; Meeghan A Hart; Anna Marie V Kibler; Michael Rueschman; Carol L Rosen; Carolyn M Kercsmar; Susan Redline Journal: J Pediatr Date: 2011-12-01 Impact factor: 4.406
Authors: Andrea Crespo; Daniel Álvarez; Leila Kheirandish-Gozal; Gonzalo C Gutiérrez-Tobal; Ana Cerezo-Hernández; David Gozal; Roberto Hornero; Félix Del Campo Journal: Sleep Breath Date: 2018-02-16 Impact factor: 2.816