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Literature DB >> 14603001

Subfield history: Caenorhabditis elegans as a system for analysis of the genetics of aging.

Abstract

This article reviews key events in the genetic analysis of aging in the worm. The events are presented in the form of a timeline and include landmark papers, key meetings, and the development of important funding agencies. I also speculate on events that might appear in this timeline if this review were written in the distant future.

Entities: Species

Mesh：

Year: 2002 PMID： 14603001 DOI： 10.1126/sageke.2002.34.re4

Source DB: PubMed Journal: Sci Aging Knowledge Environ ISSN： 1539-6150

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Cited

5 in total

1. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

Authors: Seung Wook Oh; Arnab Mukhopadhyay; Nenad Svrzikapa; Feng Jiang; Roger J Davis; Heidi A Tissenbaum
Journal: Proc Natl Acad Sci U S A Date: 2005-03-14 Impact factor: 11.205

Subfield history: Caenorhabditis elegans as a system for analysis of the genetics of aging.

1. JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16.

2. Pharmacological intervention in invertebrate aging.

3. Loss of intestinal nuclei and intestinal integrity in aging C. elegans.

4. Translational geroscience: emphasizing function to achieve optimal longevity.

Review 5. Bioactive Phytochemicals with Anti-Aging and Lifespan Extending Potentials in Caenorhabditis elegans.