Fernando Guerrero-Romero1, Martha Rodríguez-Morán. 1. Unidad Médica de Investigación en Epidemiología Clínica, Instituto Mexicano del Seguro Social, Durango, Mexico. guerrero_romero@hotmail.com
Abstract
BACKGROUND: Our objective was to develop an anthropometric-based index (abdominal volume index, AVI) for estimating overall abdominal volume and to determine its relationship with presence of impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM). METHODS: We conducted a cross-sectional, population-based study between November 1998 and June 2001 among 746 men and non-pregnant women randomly recruited from Durango City in northern Mexico. AVI was calculated using volume formulas for cylinder (V=pir2h) and vertical cone V=(1/3)pir2h. The formula developed was AVI=[2 cm (waist)2+0.7 cm (waist-hip)2]/1,000, which estimates overall abdominal volume between symphysis of pubis and xiphoid appendix and theoretically includes intra-abdominal fat and adipose tissue volumes. RESULTS: Receiver operating curve (ROC) scatter plot showed as best cut-off value of AVI for estimation of obesity, corresponding to 24.5 liters (L). Logistic regression analysis adjusted by age and sex showed higher odds ratio between AVI and IGT 1.6 (95% confidence interval [95% CI] 1.1-9.1, p=0.01) as well as between AVI and DM 2.1 (95% CI 1.3-7.9, p=0.001) than odds ratio (OR) estimated by other anthropometric obesity criteria such as waist-to-hip ratio, body mass index, truncated cone, and waist circumference. CONCLUSIONS: AVI is a reliable and easy-to-calculate anthropometric tool for estimation of overall abdominal volume that is shown to be strongly related to IGT and DM.
BACKGROUND: Our objective was to develop an anthropometric-based index (abdominal volume index, AVI) for estimating overall abdominal volume and to determine its relationship with presence of impaired glucose tolerance (IGT) and type 2 diabetes mellitus (DM). METHODS: We conducted a cross-sectional, population-based study between November 1998 and June 2001 among 746 men and non-pregnant women randomly recruited from Durango City in northern Mexico. AVI was calculated using volume formulas for cylinder (V=pir2h) and vertical cone V=(1/3)pir2h. The formula developed was AVI=[2 cm (waist)2+0.7 cm (waist-hip)2]/1,000, which estimates overall abdominal volume between symphysis of pubis and xiphoid appendix and theoretically includes intra-abdominal fat and adipose tissue volumes. RESULTS: Receiver operating curve (ROC) scatter plot showed as best cut-off value of AVI for estimation of obesity, corresponding to 24.5 liters (L). Logistic regression analysis adjusted by age and sex showed higher odds ratio between AVI and IGT 1.6 (95% confidence interval [95% CI] 1.1-9.1, p=0.01) as well as between AVI and DM 2.1 (95% CI 1.3-7.9, p=0.001) than odds ratio (OR) estimated by other anthropometric obesity criteria such as waist-to-hip ratio, body mass index, truncated cone, and waist circumference. CONCLUSIONS: AVI is a reliable and easy-to-calculate anthropometric tool for estimation of overall abdominal volume that is shown to be strongly related to IGT and DM.
Authors: Paolo Sorino; Angelo Campanella; Caterina Bonfiglio; Antonella Mirizzi; Isabella Franco; Antonella Bianco; Maria Gabriella Caruso; Giovanni Misciagna; Laura R Aballay; Claudia Buongiorno; Rosalba Liuzzi; Anna Maria Cisternino; Maria Notarnicola; Marisa Chiloiro; Francesca Fallucchi; Giovanni Pascoschi; Alberto Rubén Osella Journal: Sci Rep Date: 2021-10-12 Impact factor: 4.379
Authors: Kiymet Bozaoglu; Chantal Attard; Hemant Kulkarni; Nik Cummings; Vincent P Diego; Melanie A Carless; Katherine A Shields; Matthew P Johnson; Sudhir Kowlessur; Thomas D Dyer; Anthony G Comuzzie; Laura Almasy; Paul Zimmet; Eric K Moses; Harald H H Göring; Joanne E Curran; John Blangero; Jeremy B M Jowett Journal: J Clin Endocrinol Metab Date: 2014-06-10 Impact factor: 5.958