Literature DB >> 14602271

Prevention of postoperative paraplegia during thoracoabdominal aortic surgery.

Yukio Kuniyoshi1, Kageharu Koja, Kazufumi Miyagi, Mituyoshi Shimoji, Tooru Uezu, Katuya Arakaki, Satoshi Yamashiro, Katuhito Mabuni, Shigenobu Senaha, Yoshiyuki Nakasone.   

Abstract

BACKGROUND: We present data showing the impact of sequential multisegmental aortic clamping accompanied by reimplantation of as many segmental arteries as possible on the prevention of postoperative paraplegia or paraparesis during thoracoabdominal aortic graft replacement.
METHODS: Since 1987 we have performed graft replacements in 51 individuals undergoing thoracoabdominal aortic surgery using the technique of normothermic partial bypass with sequential multisegmental aortic clamping. The procedure was performed emergently in 10 patients and electively in 41 patients. The patients ranged in age from 22 to 82 years (mean, 57.6 +/- 13.8 years). Indications for surgery included dissecting thoracoabdominal aortic aneurysm (n = 19) and nondissecting thoracoabdominal aortic aneurysm (n = 32). The extent of aneurysm was Crawford type I in 19 patients, type II in 7 patients, type III in 12 patients, and type IV in 13 patients. Along the entire extent of aneurysm to be replaced, we reimplanted as many of the patent segmental arteries as feasible.
RESULTS: Five patients died during hospitalization, for an in-hospital mortality rate of 9.8%. The number of aortic clampings per patient ranged from one to five (median, three). A total of 124 segmental arteries were reimplanted in 44 (86.3%) of 51 patients. Of the 124 arteries, 90 (72.6%) were distributed between T9 and L2. Postoperative paraplegia or paraparesis did not develop in any of the patients.
CONCLUSIONS: Our results demonstrate that extensive reimplantation of segmental arteries using sequential multisegmental aortic clamping, accompanied by adequate intraoperative distal aortic perfusion, is effective in preventing spinal cord ischemia.

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Year:  2003        PMID: 14602271     DOI: 10.1016/s0003-4975(03)00871-3

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  5 in total

Review 1.  Current strategies for spinal cord protection during thoracic and thoracoabdominal aortic aneurysm repair.

Authors:  Hideyuki Shimizu; Ryohei Yozu
Journal:  Gen Thorac Cardiovasc Surg       Date:  2011-03-30

2.  Neuroprotective effects of PEP-1-Cu,Zn-SOD against ischemic neuronal damage in the rabbit spinal cord.

Authors:  Woosuk Kim; Dae Won Kim; Dae Young Yoo; Jin Young Chung; In Koo Hwang; Moo-Ho Won; Soo Young Choi; Sei Woong Jeon; Je Hoon Jeong; Hyung Sik Hwang; Seung Myung Moon
Journal:  Neurochem Res       Date:  2011-10-02       Impact factor: 3.996

3.  Effects of adenosine monophosphate-activated kinase in the ventral horn of rabbit spinal cord after transient ischemia.

Authors:  Byung Moon Cho; Woosuk Kim; Dae Young Yoo; Hyo Young Jung; Jung Hoon Choi; Moo-Ho Won; In Koo Hwang; Seung Myung Moon
Journal:  J Spinal Cord Med       Date:  2014-05-03       Impact factor: 1.985

4.  Hypoxic preconditioning increases the protective effect of bone marrow mesenchymal stem cells on spinal cord ischemia/reperfusion injury.

Authors:  Zhilin Wang; Bo Fang; Zhibin Tan; Dong Zhang; Hong Ma
Journal:  Mol Med Rep       Date:  2016-01-11       Impact factor: 2.952

5.  Ischemic preconditioning protects against spinal cord ischemia-reperfusion injury in rabbits by attenuating blood spinal cord barrier disruption.

Authors:  Bo Fang; Xiao-Man Li; Xi-Jia Sun; Na-Ren Bao; Xiao-Yan Ren; Huang-Wei Lv; Hong Ma
Journal:  Int J Mol Sci       Date:  2013-05-17       Impact factor: 5.923

  5 in total

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