Literature DB >> 14602015

Synthesis of dimethyl sulfomycinamate.

Mark C Bagley1, James W Dale, Xin Xiong, Justin Bower.   

Abstract

[reaction: see text] Dimethyl sulfomycinamate, the oxazole-thiazole-pyridine product generated in the methanolysis of the thiopeptide antibiotic sulfomycin I, is prepared in 13 steps and 8% overall yield by the Bohlmann-Rahtz heteroannulation of 1-(oxazol-4-yl)enamines and methyl 4-(trimethylsilyl)-2-oxobut-3-ynoate.

Entities:  

Year:  2003        PMID: 14602015     DOI: 10.1021/ol0357144

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  2 in total

Review 1.  Thiopeptide antibiotics: retrospective and recent advances.

Authors:  Xavier Just-Baringo; Fernando Albericio; Mercedes Álvarez
Journal:  Mar Drugs       Date:  2014-01-17       Impact factor: 5.118

2.  Beta-enamino esters in heterocyclic synthesis: synthesis of pyrazolone and pyridinone derivatives.

Authors:  Abdellatif Mohamed Salaheldin; Mariam Abdullah Al-Sheikh
Journal:  Molecules       Date:  2010-06-15       Impact factor: 4.411

  2 in total

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