Literature DB >> 14601850

Transpupillary thermotherapy for treatment of choroidal neovascularization secondary to age-related macular degeneration in Indian eyes.

Manish Nagpal1, Kamal Nagpal, Shobhana Sharma, Jyoti Puri, Pran N Nagpal.   

Abstract

AIM: To evaluate the efficacy of transpupillary thermotherapy (TTT) for treatment of subfoveal choroidal neovascularisation (CNV) secondary to age-related macular degeneration (AMD), and to define accurate power settings for this procedure in Indian eyes.
METHODS: A prospective, nonrandomised study of 160 eyes of 144 patients with subfoveal CNV. The laser settings included 2 mm spot and 300 mw power or 3 mm spot and 400-600 mw power. Two separate 3 mm spots were used in larger lesions. The treatment was given for 60 seconds at each point.
RESULTS: Ninety-nine eyes had classic membranes and 61 eyes had occult membranes. Following treatment, 79 of 99 (79.8%) classic and 52 of 61 (85%) occult membranes regressed. Visual improvement (> or = 2 lines) was seen in 29 (29.3%) eyes and 12 (19.6%) eyes; visual stabilisation (1 line) in 39 (39.4%) eyes, and 35 (57.4%) eyes; and reduction of vision (< or = 2 lines) in 31 (31.3%) eyes and 14 (22.9%) eyes with classic and occult membranes respectively. Mean follow-up was 12 months. One patient suffered inadvertant foveal burn.
CONCLUSION: TTT is effective in the management of subfoveal membranes in Indian eyes. They respond to lower energy levels compared to the Caucasian eyes.

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Year:  2003        PMID: 14601850

Source DB:  PubMed          Journal:  Indian J Ophthalmol        ISSN: 0301-4738            Impact factor:   1.848


  3 in total

1.  Long term results after transpupillary thermotherapy in eyes with occult choroidal neovascularisation associated with age related macular degeneration: a prospective trial.

Authors:  U Stolba; I Krebs; P D Lamar; T Aggermann; D Gruber; S Binder
Journal:  Br J Ophthalmol       Date:  2006-02       Impact factor: 4.638

2.  Relationship between intensity of reflected light and temperature increase: assessment of fundus pigmentation for transpupillary thermotherapy.

Authors:  Ryo Obata; Yasuhiro Tamaki; Yasuo Yanagi; Junko Kami
Journal:  Jpn J Ophthalmol       Date:  2007-12-21       Impact factor: 2.447

3.  Large spot transpupillary thermotherapy: a quicker laser for treatment of high risk prethreshold retinopathy of prematurity - a randomized study.

Authors:  Parag K Shah; V Narendran; N Kalpana
Journal:  Indian J Ophthalmol       Date:  2011 Mar-Apr       Impact factor: 1.848

  3 in total

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