Matthias Zehnder1, Matthias Grawehr, Gunnar Hasselgren, Tuomas Waltimo. 1. University of Zürich, University of Zürich Center for Dental Medicine, Division of Preventive Dentistry, Cariology and Periodontology, Zürich, Switzerland. zehnder@zzmk.unizh.ch
Abstract
OBJECTIVE: The goal of this study was to compare the tissue-dissolution potential and antibacterial effectiveness of a conventional Ca(OH)(2)/saline paste with equivalent Ca(OH)(2)/NaOCl and Ca(OH)(2)/chlorhexidine digluconate medications. STUDY DESIGN: Tissue specimens were obtained from freshly dissected pig palates. Tissue pieces of similar form and weight were incubated in air-tight containers with Ca(OH)(2) pastes or solutions proper for up to 7 days. Antimicrobial testing was performed in dentin blocks infected with Enterococcus faecalis. Medicated, sealed dentin specimens were incubated for 1 and 5 days, and bacterial growth was tested at different dentin depths. RESULTS: Up to day 4, the Ca(OH)(2)/irrigating solution mixtures dissolved tissue more effectively than the conventional Ca(OH)(2)/saline paste. After 7 days, however, no statistically significant differences were found between the saline and hypochlorite mixtures, but the Ca(OH)(2)/chlorhexidine medication was significantly less effective. Dentin block disinfection was quicker and more thorough with the Ca(OH)(2)/chlorhexidine or the Ca(OH)(2)/NaOCl than with the Ca(OH)(2)/saline paste. CONCLUSION: Ca(OH)(2)/irrigant mixtures under investigation appear more advantageous than the conventional Ca(OH)(2)/saline mixture, and merit further investigation in a clinical study.
OBJECTIVE: The goal of this study was to compare the tissue-dissolution potential and antibacterial effectiveness of a conventional Ca(OH)(2)/saline paste with equivalent Ca(OH)(2)/NaOCl and Ca(OH)(2)/chlorhexidine digluconate medications. STUDY DESIGN: Tissue specimens were obtained from freshly dissected pig palates. Tissue pieces of similar form and weight were incubated in air-tight containers with Ca(OH)(2) pastes or solutions proper for up to 7 days. Antimicrobial testing was performed in dentin blocks infected with Enterococcus faecalis. Medicated, sealed dentin specimens were incubated for 1 and 5 days, and bacterial growth was tested at different dentin depths. RESULTS: Up to day 4, the Ca(OH)(2)/irrigating solution mixtures dissolved tissue more effectively than the conventional Ca(OH)(2)/saline paste. After 7 days, however, no statistically significant differences were found between the saline and hypochlorite mixtures, but the Ca(OH)(2)/chlorhexidine medication was significantly less effective. Dentin block disinfection was quicker and more thorough with the Ca(OH)(2)/chlorhexidine or the Ca(OH)(2)/NaOCl than with the Ca(OH)(2)/saline paste. CONCLUSION:Ca(OH)(2)/irrigant mixtures under investigation appear more advantageous than the conventional Ca(OH)(2)/saline mixture, and merit further investigation in a clinical study.
Authors: Rizwan Jouhar; Muhammad Adeel Ahmed; Hussain Abdulmuttalib Ali Almomen; Abdullah Amin Jawad BuHulayqah; Mohammed Yousef Ahmed Alkashi; Ahmed Adel A Al-Quraini; Naseer Ahmed Journal: Int J Environ Res Public Health Date: 2022-05-28 Impact factor: 4.614
Authors: Cláudia Fernandes de Magalhães Silveira; Rodrigo Sanches Cunha; Carlos Eduardo Fontana; Alexandre Sigrist de Martin; Brenda Paula Figueiredo de Almeida Gomes; Rogério Heládio Lopes Motta; Carlos Eduardo da Silveira Bueno Journal: Eur J Dent Date: 2011-01