Literature DB >> 14599629

Association between cardiac and noncardiac complications in patients undergoing noncardiac surgery: outcomes and effects on length of stay.

Kirsten E Fleischmann1, Lee Goldman, Belinda Young, Thomas H Lee.   

Abstract

PURPOSE: To determine the relation between cardiac and noncardiac complications and their effects on length of stay in patients undergoing noncardiac surgery.
METHODS: We collected detailed information from the history, physical examination, and preoperative tests of 3970 patients aged > or =50 years who were undergoing major noncardiac procedures. Serial electrocardiograms and cardiac enzyme measurements were performed perioperatively, and cardiac and noncardiac complications were recorded prospectively. Multivariate logistic regression analysis was used to determine the association between cardiac and noncardiac complications, and linear regression was used to assess their effects on length of stay.
RESULTS: Cardiac complications occurred in 84 patients (2%), and noncardiac complications developed in 510 patients (13%). Both types of complications occurred in 40 patients (1%). The most common cardiac complications were pulmonary edema (n = 42) and myocardial infarction (n = 41). The most common noncardiac complications were wound infection (n = 291), confusion (n = 87), respiratory failure requiring intubation (n = 62), deep venous thrombosis (n = 48), and bacterial pneumonia (n = 46). Patients with cardiac complications were more likely to suffer a noncardiac complication than were those without cardiac complications, even after adjustment for preoperative clinical factors (odds ratio = 6.4; 95% confidence interval [CI]: 3.9 to 10.6). Mean length of stay was markedly increased in patients who experienced cardiac (11 days; 95% CI: 9 to 12 days) or noncardiac (11 days; 95% CI: 10 to 12 days) complications, or both (15 days; 95% CI: 12 to 18 days), as compared with patients without complications (4 days; 95% CI: 3 to 4 days), even after adjustment for procedure type and clinical factors.
CONCLUSION: Cardiac and noncardiac complications were strongly linked in patients undergoing noncardiac surgery. Patients who experienced one type of complication were at increased risk of developing the other type of complication as well as prolonged perioperative length of stay.

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Mesh:

Year:  2003        PMID: 14599629     DOI: 10.1016/s0002-9343(03)00474-1

Source DB:  PubMed          Journal:  Am J Med        ISSN: 0002-9343            Impact factor:   4.965


  43 in total

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Authors:  P J Devereaux; Lee Goldman; Deborah J Cook; Ken Gilbert; Kate Leslie; Gordon H Guyatt
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Review 4.  Surveillance and prevention of major perioperative ischemic cardiac events in patients undergoing noncardiac surgery: a review.

Authors:  P J Devereaux; Lee Goldman; Salim Yusuf; Ken Gilbert; Kate Leslie; Gordon H Guyatt
Journal:  CMAJ       Date:  2005-09-27       Impact factor: 8.262

Review 5.  [Minimizing perioperative risk - an interdisciplinary effort].

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8.  Non-invasive cardiac stress testing before elective major non-cardiac surgery: population based cohort study.

Authors:  Duminda N Wijeysundera; W Scott Beattie; Peter C Austin; Janet E Hux; Andreas Laupacis
Journal:  BMJ       Date:  2010-01-28

9.  Antimicrobial prophylaxis in colorectal surgery: focus on ertapenem.

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10.  Is Peri-Operative Isolated Systolic Hypertension (ISH) a Cardiac Risk Factor?

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Journal:  Curr Cardiol Rev       Date:  2008-02
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