Literature DB >> 14599526

Antioxidant flavonoids from the rhizomes of Helminthostachys zeylanica.

Yu-Ling Huang1, Pei-Yu Yeh, Chien-Chang Shen, Chien-Chih Chen.   

Abstract

Eight flavonoids, ugonins E-L (1-8), were isolated from the rhizomes of Helminthostachys zeylanica, and their structures were established on the basis of spectral evidence. Compounds 3-8 were evaluated for their antioxidative activity in the 1, 1-diphenyl-2-picrylhydrazyl (DPPH) assay. Compounds 6, 7 and 8 were more active than Trolox, with IC20 values of 5.29 +/- 0.32, 7.23 +/- 0.22, and 7.93 +/- 0.31, respectively.

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Year:  2003        PMID: 14599526     DOI: 10.1016/j.phytochem.2003.09.009

Source DB:  PubMed          Journal:  Phytochemistry        ISSN: 0031-9422            Impact factor:   4.072


  6 in total

1.  Novel quercetin glucosides from Helminthostachys zeylanica root and acceleratory activity of melanin biosynthesis.

Authors:  Kosei Yamauchi; Tohru Mitsunaga; Irmanida Batubara
Journal:  J Nat Med       Date:  2012-05-13       Impact factor: 2.343

2.  Neuroprotective effects of ugonin K on hydrogen peroxide-induced cell death in human neuroblastoma SH-SY5Y cells.

Authors:  Yi-Chien Lin; Yaun-Chao Huang; Sheng-Chih Chen; Chih-Chuang Liaw; Sheng-Chu Kuo; Li-Jiau Huang; Po-Wu Gean
Journal:  Neurochem Res       Date:  2008-10-08       Impact factor: 3.996

3.  Evaluation of Anti-Inflammatory Effects of Helminthostachys zeylanica Extracts via Inhibiting Bradykinin-Induced MMP-9 Expression in Brain Astrocytes.

Authors:  Chuen-Mao Yang; Sien-Hung Yang; Tsong-Hai Lee; Jia-You Fang; Chwan-Fwu Lin; Mei-Jie Jou; Hsi-Lung Hsieh
Journal:  Mol Neurobiol       Date:  2015-11-02       Impact factor: 5.590

4.  Ugonin M, a Helminthostachys zeylanica Constituent, Prevents LPS-Induced Acute Lung Injury through TLR4-Mediated MAPK and NF-κB Signaling Pathways.

Authors:  Kun-Chang Wu; Shyh-Shyun Huang; Yueh-Hsiung Kuo; Yu-Ling Ho; Chang-Syun Yang; Yuan-Shiun Chang; Guan-Jhong Huang
Journal:  Molecules       Date:  2017-04-01       Impact factor: 4.411

5.  Hepatoprotective Effect of Ugonin M, A Helminthostachyszeylanica Constituent, on Acetaminophen-Induced Acute Liver Injury in Mice.

Authors:  Kun-Chang Wu; Yu-Ling Ho; Yueh-Hsiung Kuo; Shyh-Shyun Huang; Guan-Jhong Huang; Yuan-Shiun Chang
Journal:  Molecules       Date:  2018-09-21       Impact factor: 4.411

6.  Quality Control of the Root and Rhizome of Helminthostachys zeylanica (Daodi-Ugon) by HPLC Using Quercetin and Ugonins as Markers.

Authors:  Kun-Chang Wu; Chun-Pin Kao; Yu-Ling Ho; Yuan-Shiun Chang
Journal:  Molecules       Date:  2017-07-05       Impact factor: 4.411

  6 in total

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