Literature DB >> 14599009

The mechanism of 7,8-diaminopelargonate synthase; the role of S-adenosylmethionine as the amino donor.

Rachel S Breen1, Dominic J Campopiano, Scott Webster, Mhairi Brunton, Rory Watt, Robert L Baxter.   

Abstract

The product of the first transamination step in the reaction catalysed by diaminopelargonate (DAPA) synthase has been shown to be 4-(S-adenosyl)-2-oxobutanoate, which has been trapped as the corresponding alcohol.

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Year:  2003        PMID： 14599009     DOI： 10.1039/b310443p

Source DB:  PubMed          Journal:  Org Biomol Chem        ISSN： 1477-0520            Impact factor:   3.876


  4 in total

1.  Structural characterization of the Mycobacterium tuberculosis biotin biosynthesis enzymes 7,8-diaminopelargonic acid synthase and dethiobiotin synthetase .

Authors:  Sanghamitra Dey; James M Lane; Richard E Lee; Eric J Rubin; James C Sacchettini
Journal:  Biochemistry       Date:  2010-08-10       Impact factor: 3.162

2.  Biochemical and structural characterization of the Arabidopsis bifunctional enzyme dethiobiotin synthetase-diaminopelargonic acid aminotransferase: evidence for substrate channeling in biotin synthesis.

Authors:  David Cobessi; Renaud Dumas; Virginie Pautre; Céline Meinguet; Jean-Luc Ferrer; Claude Alban
Journal:  Plant Cell       Date:  2012-04-30       Impact factor: 11.277

3.  A surprising range of modified-methionyl S-adenosylmethionine analogues support bacterial growth.

Authors:  Mojun Zhao; Yasanandana S Wijayasinghe; Pravin Bhansali; Ronald E Viola; Robert M Blumenthal
Journal:  Microbiology       Date:  2015-03       Impact factor: 2.777

4.  Revisiting the methionine salvage pathway and its paralogues.

Authors:  Agnieszka Sekowska; Hiroki Ashida; Antoine Danchin
Journal:  Microb Biotechnol       Date:  2018-10-10       Impact factor: 5.813
  4 in total

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