Literature DB >> 14598063

Proteome analysis of mesencephalic tissues: evidence for Parkinson's disease.

M Basso1, S Giraudo, L Lopiano, B Bergamasco, E Bosticco, A Cinquepalmi, M Fasano.   

Abstract

Proteome analysis is a powerful methodology to investigate protein expression in tissues involved in diseases not linked to particular genetic defects. To date, this technique has a limited number of applications in the field of neurodegenerative disorders. We decided therefore to investigate by this approach autoptic mesencephalic tissues of patients with idiopathic Parkinson's disease as well as control specimens from healthy subjects.

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Year:  2003        PMID: 14598063     DOI: 10.1007/s10072-003-0106-2

Source DB:  PubMed          Journal:  Neurol Sci        ISSN: 1590-1874            Impact factor:   3.307


  3 in total

1.  Electrophilic adduction of ubiquitin activating enzyme E1 by N,N-diethyldithiocarbamate inhibits ubiquitin activation and is accompanied by striatal injury in the rat.

Authors:  Olga M Viquez; Samuel W Caito; W Hayes McDonald; David B Friedman; William M Valentine
Journal:  Chem Res Toxicol       Date:  2012-08-22       Impact factor: 3.739

Review 2.  Advances in imaging ultrastructure yield new insights into presynaptic biology.

Authors:  Joseph J Bruckner; Hong Zhan; Kate M O'Connor-Giles
Journal:  Front Cell Neurosci       Date:  2015-05-22       Impact factor: 5.505

3.  Proteomic Characterization of Synaptosomes from Human Substantia Nigra Indicates Altered Mitochondrial Translation in Parkinson's Disease.

Authors:  Sarah Plum; Britta Eggers; Stefan Helling; Markus Stepath; Carsten Theiss; Renata E P Leite; Mariana Molina; Lea T Grinberg; Peter Riederer; Manfred Gerlach; Caroline May; Katrin Marcus
Journal:  Cells       Date:  2020-12-02       Impact factor: 6.600

  3 in total

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