Se Youp Lee1, Sherwin J Isenberg. 1. Department of Ophthalmology, Jules Stein Eye Institute, University of California Los Angeles School of Medicine, Los Angeles, California 90095, USA.
Abstract
PURPOSE: To investigate the relationship between visual acuity (VA) and stereoacuity after occlusion therapy in patients with various types of amblyopia. DESIGN: Retrospective noncomparative case series. PARTICIPANTS: Sixty-one children with amblyopia caused by anisometropia with no strabismus (26 children), small angle (</=8 prism diopters) or intermittent strabismus (20), or both (15). METHODS: All were treated with occlusion therapy. Visual acuity and near stereopsis using the Titmus test (Stereo Optical Inc., Chicago, IL) were measured at each clinic visit. MAIN OUTCOME MEASURE: The change in near stereopsis relative to distance VA after occlusion therapy. RESULTS: Mean age at initiation of therapy was 5.1 years (range = 3.5-8) and mean follow-up 52.3 weeks (range = 13-192). Mean duration of occlusion was 36 weeks (range = 12-102). After occlusion treatment, mean VA of all children improved from 0.43 to 0.78 (P<0.0001), whereas mean stereoacuity improved from 1167.4 seconds of arc to 101 (P<0.0001). By the last visit, 85.2% (52 of 61) of patients demonstrated at least 2 lines of improvement in VA. There was a significant linear relationship between VA and stereoacuity (P<0.001). The 26 anisometropic patients without strabismus enjoyed improvement in VA and stereopsis (P<0.0001) similar to that of the 35 with small-angle or intermittent strabismus (P<0.0001). CONCLUSIONS: When employing occlusion therapy for amblyopia (due to anisometropia, small-angle or intermittent strabismus, or a combination), as VA improves, stereopsis generally also improves.
PURPOSE: To investigate the relationship between visual acuity (VA) and stereoacuity after occlusion therapy in patients with various types of amblyopia. DESIGN: Retrospective noncomparative case series. PARTICIPANTS: Sixty-one children with amblyopia caused by anisometropia with no strabismus (26 children), small angle (</=8 prism diopters) or intermittent strabismus (20), or both (15). METHODS: All were treated with occlusion therapy. Visual acuity and near stereopsis using the Titmus test (Stereo Optical Inc., Chicago, IL) were measured at each clinic visit. MAIN OUTCOME MEASURE: The change in near stereopsis relative to distance VA after occlusion therapy. RESULTS: Mean age at initiation of therapy was 5.1 years (range = 3.5-8) and mean follow-up 52.3 weeks (range = 13-192). Mean duration of occlusion was 36 weeks (range = 12-102). After occlusion treatment, mean VA of all children improved from 0.43 to 0.78 (P<0.0001), whereas mean stereoacuity improved from 1167.4 seconds of arc to 101 (P<0.0001). By the last visit, 85.2% (52 of 61) of patients demonstrated at least 2 lines of improvement in VA. There was a significant linear relationship between VA and stereoacuity (P<0.001). The 26 anisometropic patients without strabismus enjoyed improvement in VA and stereopsis (P<0.0001) similar to that of the 35 with small-angle or intermittent strabismus (P<0.0001). CONCLUSIONS: When employing occlusion therapy for amblyopia (due to anisometropia, small-angle or intermittent strabismus, or a combination), as VA improves, stereopsis generally also improves.
Authors: David K Wallace; Elizabeth L Lazar; Michele Melia; Eileen E Birch; Jonathan M Holmes; Kristine B Hopkins; Raymond T Kraker; Marjean T Kulp; Yi Pang; Michael X Repka; Susanna M Tamkins; Katherine K Weise Journal: J AAPOS Date: 2011-10 Impact factor: 1.220
Authors: Catherine M Suttle; Dean R Melmoth; Alison L Finlay; John J Sloper; Simon Grant Journal: Invest Ophthalmol Vis Sci Date: 2011-03-01 Impact factor: 4.799
Authors: Simon Grant; Catherine Suttle; Dean R Melmoth; Miriam L Conway; John J Sloper Journal: Invest Ophthalmol Vis Sci Date: 2014-08-05 Impact factor: 4.799