Literature DB >> 14595279

Comparing a mechanical device with medicinal leeches for treating venous congestion.

Gregory K Hartig1, Nadine P Connor, Dennis M Heisey, Michael L Conforti.   

Abstract

OBJECTIVE: To compare mechanical device therapy to medicinal leech therapy for treating venous congestion. STUDY
DESIGN: Fasciocutaneous flaps of 9 x 7-cm (porcine model, n = 11) were elevated and the associated veins clamped for 15 hours. Device-treated flaps (n = 6) were treated with up to 3 devices/flap. Leech-treated flaps (n = 5) were treated with 75 leeches/flap (5 leeches/hour). Treatment evaluation parameters included: blood volume removed, skin color, surface perfusion, tissue oxygen tension, and endpoint histology.
RESULTS: No significant differences were seen in blood volume removed, surface perfusion, and oxygen tension. However, significant differences were seen in skin color change over time. Histological assessment showed mild congestion in 5/5 leech-treated flaps and 2/6 device-treated flaps.
CONCLUSION: Device therapy was comparable to leech therapy for decongesting a 9 x 7-cm flap over a 15-hour period. However, digital images and significant differences in skin color change over time demonstrate that device therapy promotes more global decongestion versus leech therapy.

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Year:  2003        PMID: 14595279     DOI: 10.1016/S0194-59980301587-0

Source DB:  PubMed          Journal:  Otolaryngol Head Neck Surg        ISSN: 0194-5998            Impact factor:   5.591


  1 in total

1.  Experience with pharmacologic leeching with bivalirudin for adjunct treatment of venous congestion of head and neck reconstructive flaps.

Authors:  Aisha Harun; Rachel M Kruer; Andrew Lee; Kofi Boahene; Patrick J Byrne; Jeremy D Richmon
Journal:  Microsurgery       Date:  2018-01-18       Impact factor: 2.425

  1 in total

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