Literature DB >> 145950

Effects of streptozotocin on early rat embryos grown in culture.

E M Deuchar.   

Abstract

Addition of 1 mg/ml streptozotocin to serum in which 10-day rat embryos are cultured reduces their growth and viability. There is therefore a risk that administration of this drug to pregnant animals to induce diabetes could also have direct, deleterious effects on the embryos.

Entities:  

Mesh:

Substances:

Year:  1978        PMID: 145950     DOI: 10.1007/bf01921917

Source DB:  PubMed          Journal:  Experientia        ISSN: 0014-4754


  8 in total

Review 1.  Drugs producing diabetes through damage of the insulin secreting cells.

Authors:  C C Rerup
Journal:  Pharmacol Rev       Date:  1970-12       Impact factor: 25.468

2.  The mechanism of axial rotation in the rat embryo: an experimental study in vitro.

Authors:  E M Deuchar
Journal:  J Embryol Exp Morphol       Date:  1971-04

3.  Use of streptozotocin as diabetic agent in pregnant rats.

Authors:  S Sybulski; G B Maughan
Journal:  Endocrinology       Date:  1971-12       Impact factor: 4.736

4.  [Behavior of rats with chronic streptozotocin diabetes].

Authors:  B Rudas
Journal:  Klin Wochenschr       Date:  1969-10-15

5.  Streptozotocin diabetes in pregnant and nonpregnant rats.

Authors:  E K Golob; S Rishi; K L Becker; C Moore
Journal:  Metabolism       Date:  1970-12       Impact factor: 8.694

6.  Development of rat embryos cultured in blood sera.

Authors:  D A New
Journal:  J Reprod Fertil       Date:  1966-12

7.  Embryonic malformations in rats, resulting from maternal diabetes: preliminary observations.

Authors:  E M Deuchar
Journal:  J Embryol Exp Morphol       Date:  1977-10

8.  Streptozotocin: its excretion and metabolism in the rat.

Authors:  E H Karunanayake; D J Hearse; G Mellows
Journal:  Diabetologia       Date:  1976-10       Impact factor: 10.122

  8 in total
  2 in total

Review 1.  Diabetes in pregnancy 1985.

Authors:  D R Hadden
Journal:  Diabetologia       Date:  1986-01       Impact factor: 10.122

2.  Fetal diabetes in rats and its effect on placental glycogen.

Authors:  V Barash; A Gutman; E Shafrir
Journal:  Diabetologia       Date:  1985-04       Impact factor: 10.122

  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.