Literature DB >> 14593222

Prophet in his own country: Carlos Chagas and the Nobel Prize.

Rachel Lewinsohn1.   

Abstract

In 1909, Carlos Chagas (1878-1934) discovered a new protozoon, Trypanosoma cruzi, and the (previously unknown) disease that it causes. Within a few months, virtually single-handed, he described the pathogen, its vector, and the clinical features of American trypanosomiasis (Chagas disease), a feat unique in medical history. He headed the Oswaldo Cruz Institute after the death of its founder (1917) until his own death; and from 1920 until 1926 he also directed the Brazilian Department of Public Health. His discovery brought him worldwide acclaim, but at home antagonism against Chagas, muted for years, finally flared up in a campaign that was acted out in the 1921-22 plenary sessions of the National Academy of Medicine. Chagas's name was repeatedly proposed for the Nobel Prize but he never received it; this hostile campaign may have been instrumental in costing him the award.

Entities:  

Mesh:

Year:  2003        PMID: 14593222     DOI: 10.1353/pbm.2003.0078

Source DB:  PubMed          Journal:  Perspect Biol Med        ISSN: 0031-5982            Impact factor:   1.416


  5 in total

1.  Human autoantibodies specific for neurotrophin receptors TrkA, TrkB, and TrkC protect against lethal Trypanosoma cruzi infection in mice.

Authors:  Bo Lu; Joseph Alroy; Alejandro O Luquetti; Mercio PereiraPerrin
Journal:  Am J Pathol       Date:  2008-10-02       Impact factor: 4.307

2.  Commentary: Chagas disease: 100 years since discovery and lessons for the future.

Authors:  Ricardo E Gürtler; Liléia Diotaiuti; Uriel Kitron
Journal:  Int J Epidemiol       Date:  2008-08       Impact factor: 7.196

Review 3.  Perspectives on Trypanosoma cruzi-induced heart disease (Chagas disease).

Authors:  Herbert B Tanowitz; Fabiana S Machado; Linda A Jelicks; Jamshid Shirani; Antonio C Campos de Carvalho; David C Spray; Stephen M Factor; Louis V Kirchhoff; Louis M Weiss
Journal:  Prog Cardiovasc Dis       Date:  2009 May-Jun       Impact factor: 8.194

4.  Conventional therapy and promising plant-derived compounds against trypanosomatid parasites.

Authors:  Daniela Sales Alviano; Anna Léa Silva Barreto; Felipe de Almeida Dias; Igor de Almeida Rodrigues; Maria do Socorro Dos Santos Rosa; Celuta Sales Alviano; Rosangela Maria de Araújo Soares
Journal:  Front Microbiol       Date:  2012-08-06       Impact factor: 5.640

Review 5.  The history of Chagas disease.

Authors:  Dietmar Steverding
Journal:  Parasit Vectors       Date:  2014-07-10       Impact factor: 3.876

  5 in total

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