Literature DB >> 1459250

Beta-glucosidase activity towards a bile acid glucoside in human liver.

H Matern1, R Gartzen, S Matern.   

Abstract

Human liver contains hydrolytic activity toward 3 beta-glucosido-chenodeoxycholic acid. This beta-glucosidase activity, localized predominantly in the microsomal fraction, was optimally active in the presence of divalent metal ions close to pH 5.0 and was inhibited by EDTA. Kinetic parameters and other catalytic properties of hydrolytic activity towards 3 beta-glucosido-chenodeoxycholic acid from human liver microsomes are described.

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Year:  1992        PMID: 1459250     DOI: 10.1016/0014-5793(92)80970-r

Source DB:  PubMed          Journal:  FEBS Lett        ISSN: 0014-5793            Impact factor:   4.124


  6 in total

Review 1.  Current and Novel Aspects on the Non-lysosomal β-Glucosylceramidase GBA2.

Authors:  Aureli Massimo; Samarani Maura; Loberto Nicoletta; Mancini Giulia; Murdica Valentina; Chiricozzi Elena; Prinetti Alessandro; Bassi Rosaria; Sonnino Sandro
Journal:  Neurochem Res       Date:  2015-11-24       Impact factor: 3.996

2.  Loss of function of glucocerebrosidase GBA2 is responsible for motor neuron defects in hereditary spastic paraplegia.

Authors:  Elodie Martin; Rebecca Schüle; Katrien Smets; Agnès Rastetter; Amir Boukhris; José L Loureiro; Michael A Gonzalez; Emeline Mundwiller; Tine Deconinck; Marc Wessner; Ludmila Jornea; Andrés Caballero Oteyza; Alexandra Durr; Jean-Jacques Martin; Ludger Schöls; Chokri Mhiri; Foudil Lamari; Stephan Züchner; Peter De Jonghe; Edor Kabashi; Alexis Brice; Giovanni Stevanin
Journal:  Am J Hum Genet       Date:  2013-01-17       Impact factor: 11.025

3.  Beta-glucosidase 1 (GBA1) is a second bile acid β-glucosidase in addition to β-glucosidase 2 (GBA2). Study in β-glucosidase deficient mice and humans.

Authors:  Klaus Harzer; Yotam Blech-Hermoni; Ehud Goldin; Ursula Felderhoff-Mueser; Claudia Igney; Ellen Sidransky; Yildiz Yildiz
Journal:  Biochem Biophys Res Commun       Date:  2012-05-30       Impact factor: 3.575

4.  Mutation of beta-glucosidase 2 causes glycolipid storage disease and impaired male fertility.

Authors:  Yildiz Yildiz; Heidrun Matern; Bonne Thompson; Jeremy C Allegood; Rebekkah L Warren; Denise M O Ramirez; Robert E Hammer; F Kent Hamra; Siegfried Matern; David W Russell
Journal:  J Clin Invest       Date:  2006-11       Impact factor: 14.808

5.  Expression and crystallization of a bacterial glycoside hydrolase family 116 β-glucosidase from Thermoanaerobacterium xylanolyticum.

Authors:  Sompong Sansenya; Risa Mutoh; Ratana Charoenwattanasatien; Genji Kurisu; James R Ketudat Cairns
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-01-01       Impact factor: 1.056

Review 6.  The Enigmatic Role of GBA2 in Controlling Locomotor Function.

Authors:  Marina A Woeste; Dagmar Wachten
Journal:  Front Mol Neurosci       Date:  2017-11-28       Impact factor: 5.639

  6 in total

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