Literature DB >> 14589480

Management of postprocedural discitis.

Jeff S Silber1, D Greg Anderson, Alexander R Vaccaro, Paul A Anderson, Paul McCormick.   

Abstract

BACKGROUND CONTEXT: Fortunately, the incidence of postprocedural discitis is relatively uncommon. The paucity of physical examination findings behooves the spine care practitioner to have a high index of suspicion in any patient presenting with increasing back pain after an invasive spinal procedure. The diagnosis can often be established in a timely fashion based on the history, physical examination, laboratory studies (erythrocyte sedimentation rate, C-reactive protein and blood cultures) and imaging studies (plain radiographs, magnetic resonance imaging, computed tomography and radionuclide scanning).
PURPOSE: To review the English literature on the subject of postprocedural discitis. The incidence, pathophysiology, laboratory markers and imaging findings are discussed. Recommendations on treatment strategies are presented along with long-term clinical outcomes of this postprocedure complication.
METHODS: A contemporary English literature search of MEDLINE and PubMed on the topic of postoperative discitis was performed.
RESULTS: The incidence of postprocedural discitis is approximately 0.2%. The most common etiologic agent is Staphylococcus aureus. The C-reactive protein is the most sensitive clinical laboratory marker to assess the presence of infection and effectiveness of treatment response. Magnetic resonance imaging is the imaging modality of choice in the diagnosis of spinal infection. The majority of patients are managed adequately with organism-specific antibiotics and spinal immobilization with good long-term outcomes. Operative intervention (open biopsy followed by antibiotic treatment and spinal immobilization or debridement and reconstruction) in patients who fail to respond to nonoperative treatment or in the presence of neurologic worsening has been demonstrated.
CONCLUSION: Postprocedural discitis is a rare complication after any invasive spinal procedure. It is imperative for the treating surgeon to maintain a high index of suspicion. Appropriate laboratory and imaging studies are invaluable in establishing a timely diagnosis. In the majority of patients, antibiotic treatment along with spinal immobilization has been shown to produce good long-term outcomes. Operative intervention is rarely necessary in patients failing conservative treatment.

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Year:  2002        PMID: 14589480     DOI: 10.1016/s1529-9430(02)00203-6

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  33 in total

Review 1.  Postoperative infections of the lumbar spine: presentation and management.

Authors:  Dennis S Meredith; Christopher K Kepler; Russel C Huang; Barry D Brause; Oheneba Boachie-Adjei
Journal:  Int Orthop       Date:  2011-12-10       Impact factor: 3.075

Review 2.  Late-onset post-diskectomy tuberculosis at the same operated lumbar level: case report and review of literature.

Authors:  Iraj Lotfinia; Payman Vahedi
Journal:  Eur Spine J       Date:  2010-05-06       Impact factor: 3.134

Review 3.  Postoperative spondilodiscitis.

Authors:  Antoine Gerometta; Fabian Bittan; Juan Carlos Rodriguez Olaverri
Journal:  Int Orthop       Date:  2012-02-04       Impact factor: 3.075

4.  Pyogenic spondylodiscitis after percutaneous endoscopic lumbar discectomy.

Authors:  Kyeong-Bo Choi; Choon-Dae Lee; Sang-Ho Lee
Journal:  J Korean Neurosurg Soc       Date:  2010-11-30

Review 5.  Postoperative spinal wound infections and postprocedural diskitis.

Authors:  Saad B Chaudhary; Michael J Vives; Sushil K Basra; Mitchell F Reiter
Journal:  J Spinal Cord Med       Date:  2007       Impact factor: 1.985

6.  Single-level lumbar pyogenic spondylodiscitis treated with minimally invasive anterior debridement and fusion combined with posterior fixation via Wiltse approach.

Authors:  Yang Lin; Wen-Jian Chen; Wen-Tao Zhu; Feng Li; Huang Fang; An-Min Chen; Wei Xiong
Journal:  J Huazhong Univ Sci Technolog Med Sci       Date:  2013-10-20

7.  Management of postoperative spinal infections.

Authors:  Vishal Hegde; Dennis S Meredith; Christopher K Kepler; Russel C Huang
Journal:  World J Orthop       Date:  2012-11-18

8.  Kinetics of charged antibiotic penetration into human intervertebral discs: A numerical study.

Authors:  Qiaoqiao Zhu; Xin Gao; Na Li; Weiyong Gu; Frank Eismont; Mark D Brown
Journal:  J Biomech       Date:  2016-07-21       Impact factor: 2.712

9.  Preventing and treating discitis: cephazolin penetration in ovine lumbar intervertebral disc.

Authors:  Rebecca Walters; Razmi Rahmat; Robert Fraser; Robert Moore
Journal:  Eur Spine J       Date:  2006-07-08       Impact factor: 3.134

10.  Antibiotic penetration into rabbit nucleus pulposus with discitis.

Authors:  Liang Zhang; Jing-cheng Wang; Xin-min Feng; Wei-hua Cai; Jian-dong Yang; Ning Zhang
Journal:  Eur J Orthop Surg Traumatol       Date:  2013-09-17
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