Literature DB >> 14589469

Extramedullary sarcoid lesion mimicking intraspinal tumor.

Bikash Bose1.   

Abstract

BACKGROUND CONTEXT: Spinal sarcoidosis is rare. Most spinal sarcoid lesions are intramedullary, and only three cases of extramedullary sarcoid lesions have been reported.
PURPOSE: To describe a case of an extramedullary sarcoid lesion in a patient that did not have systemic involvement and to review the literature of spinal sarcoidosis. STUDY DESIGN/
SETTING: Case report and review of the literature. PATIENT SAMPLE: Case report. OUTCOME MEASURES: Report of resolution of symptoms. METHODS/DESCRIPTION: The patient was a 33-year-old woman who had neck pain and pain radiating to the right scapula area and down the right arm into her hand and wrist. She also complained of numbness, tingling, muscle spasms and tremors, and had difficulty with writing. Magnetic resonance imaging showed a mass that was extramedullary in the right lateral aspect of the spinal canal at the level of C5 and extending into the right C5-6 neuroforamen. Admitting diagnosis of neurofibroma was made. The patient underwent C4, C5 and C6 laminoplasty and gross total resection of an intradural extramedullary tumor. The lesion encroached on the neuroforamen on the right side involving the C6 nerve root, was grossly adherent to some of the rootlets and looked like a Schwannoma. Gross total resection of the tumor was performed. Pathological examination of the specimen showed a noncaseating granulomatosis consistent with sarcoid. Postoperative testing did not reveal systemic involvement of sarcoidosis. The patient was treated with corticosteroids.
RESULTS: The patient made a satisfactory recovery, returned to work full-time, and had no complaints of neurological symptoms.
CONCLUSIONS: An extramedullary sarcoid lesion is rare. Unlike intramedullary sarcoid lesions, it can be totally removed. If no systemic sarcoidosis is present, the patient can have a satisfactory recovery.

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Year:  2002        PMID: 14589469     DOI: 10.1016/s1529-9430(02)00185-7

Source DB:  PubMed          Journal:  Spine J        ISSN: 1529-9430            Impact factor:   4.166


  5 in total

Review 1.  Sarcoidosis of the spinal cord: literature review and report of eight cases.

Authors:  Samer Saleh; Chandan Saw; Kamel Marzouk; Om Sharma
Journal:  J Natl Med Assoc       Date:  2006-06       Impact factor: 1.798

Review 2.  Isolated intramedullary neurosarcoidosis of the thoracic spine: case report and review of the literature.

Authors:  Bradley S Duhon; Lubdha Shah; Meic H Schmidt
Journal:  Eur Spine J       Date:  2011-05-20       Impact factor: 3.134

3.  Intradural Extramedullary Sarcoidosis case report and review of literature.

Authors:  Kaushik Roy; P Tripathy; A Senapati; S K Saha
Journal:  Asian J Neurosurg       Date:  2010-01

4.  Intradural-extramedullary isolated compressive sarcoid lesion.

Authors:  Kyle A Smith; Samuel K Asante; John Clough
Journal:  Surg Neurol Int       Date:  2016-11-21

5.  Intradural Extramedullary Spinal Sarcoidosis Mimicking Meningioma.

Authors:  Sho Ishiwata; Yoichi Iizuka; Tokue Mieda; Junko Hirato; Hiromi Koshi; Yohei Kakuta; Akira Honda; Hiroyuki Sonoda; Tsuyoshi Tajika; Hirotaka Chikuda
Journal:  Case Rep Orthop       Date:  2019-08-05
  5 in total

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