Literature DB >> 1458793

A case of Raynaud's disease with uterine cancer producing interleukin-6.

A Murashima1, Y Takasaki, H Hashimoto, T Hirano, S Hirose.   

Abstract

A case of cervical cancer of the uterine producing interleukin-6(IL-6) in a patient who suffered from Raynaud's phenomenon is described. Her serum contained anti SS-A antibody. The cancer was removed surgically. High level of IL-6 activity was detected in the culture supernatant of the resected cancer cells. After operation, Raynaud's phenomenon had improved and anti SS-A antibody had disappeared. This case shows us that IL-6 produced by malignant tumour might induce autoimmune connective tissue disease-like symptoms.

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Year:  1992        PMID： 1458793     DOI： 10.1007/bf02207206

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  8 in total

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Journal:  Annu Rev Immunol       Date:  1985       Impact factor: 28.527

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Journal:  Br Med J       Date:  1967-07-22

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Authors:  M Jourdan; R Bataille; J Seguin; X G Zhang; P A Chaptal; B Klein
Journal:  Arthritis Rheum       Date:  1990-03

6.  Human B-cell differentiation factor defined by an anti-peptide antibody and its possible role in autoantibody production.

Authors:  T Hirano; T Taga; K Yasukawa; K Nakajima; N Nakano; F Takatsuki; M Shimizu; A Murashima; S Tsunasawa; F Sakiyama
Journal:  Proc Natl Acad Sci U S A       Date:  1987-01       Impact factor: 11.205

7.  Giant lymph node hyperplasia (Castleman's disease) with spontaneous production of high levels of B-cell differentiation factor activity.

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Journal:  Cancer       Date:  1989-01-15       Impact factor: 6.860

8.  Effect of B cell differentiation factor (BCDF) on biosynthesis and secretion of immunoglobulin molecules in human B cell lines.

Authors:  H Kikutani; T Taga; S Akira; H Kishi; Y Miki; O Saiki; Y Yamamura; T Kishimoto
Journal:  J Immunol       Date:  1985-02       Impact factor: 5.422
  8 in total
  2 in total

1.  A novel human glassy-cell carcinoma cell line producing IL-6 and IL-8 from uterine cervix.

Authors:  A Oki; M Nishida; T Satoh; H Tsunoda; K Kasahara; K Saijo; T Kubo; T Ohno
Journal:  In Vitro Cell Dev Biol Anim       Date:  1998-04       Impact factor: 2.416

Review 2.  Paraneoplastic rheumatic syndromes.

Authors:  H J Mitnick
Journal:  Curr Rheumatol Rep       Date:  2000-04       Impact factor: 4.686
  2 in total

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