Literature DB >> 14586558

Fetal bovine serum, but not human serum, inhibits the in vitro cytotoxicity of ET-743 (Yondelis, trabectedin), an example of potential problems for extrapolation of active drug concentrations from in vitro studies.

Gianluca Tognon1, Roberta Frapolli, Marco Zaffaroni, Eugenio Erba, Massimo Zucchetti, Glynn T Faircloth, Maurizio D'Incalci.   

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Year:  2003        PMID： 14586558     DOI： 10.1007/s00280-003-0704-y

Source DB:  PubMed          Journal:  Cancer Chemother Pharmacol        ISSN： 0344-5704            Impact factor:   3.333


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  3 in total

1.  Cocaine induces alterations in mitochondrial membrane potential and dual cell cycle arrest in rat c6 astroglioma cells.

Authors:  Ramesh B Badisa; Selina F Darling-Reed; Carl B Goodman
Journal:  Neurochem Res       Date:  2009-09-16       Impact factor: 3.996

2.  Impact of protein binding on the analytical detectability and anticancer activity of thymoquinone.

Authors:  Nahed El-Najjar; Raimo A Ketola; Teemu Nissilä; Timo Mauriala; Maxim Antopolsky; Janne Jänis; Hala Gali-Muhtasib; Arto Urtti; Heikki Vuorela
Journal:  J Chem Biol       Date:  2011-01-08

Review 3.  Limitations of drug concentrations used in cell culture studies for understanding clinical responses of NSAIDs.

Authors:  Garry G Graham; Kieran F Scott
Journal:  Inflammopharmacology       Date:  2021-09-12       Impact factor: 4.473
  3 in total

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