Literature DB >> 1458617

Changes in immunological response in tonsillectomized children. II. Decreased cellular response.

P M Moreno1, M Sanchez, M Sainz, F Gutierrez.   

Abstract

The immunological cellular response was studied in 22 children aged between 5 and 10 years. One week before and one month after tonsillectomy, the mitogenic response to phytohaemagglutinin (PHA), concanavalin (ConA) and pokeweed mitogen (PWM) was tested. Our results showed statistically significant decreases in stimulation index (SI) to PHA, ConA and PWM after tonsillectomy. This suggests that the tonsils may influence the cellular immune status in children. The higher level of preoperative activity in children with recurrent tonsillitis could be understood as the result of stimulation of lymphocytes by bacteria.

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Year:  1992        PMID: 1458617     DOI: 10.1111/j.1365-2273.1992.tb01678.x

Source DB:  PubMed          Journal:  Clin Otolaryngol Allied Sci        ISSN: 0307-7772


  4 in total

1.  Age-dependent altered proportions in subpopulations of tonsillar lymphocytes.

Authors:  W Bergler; S Adam; H J Gross; K Hörmann; R Schwartz-Albiez
Journal:  Clin Exp Immunol       Date:  1999-04       Impact factor: 4.330

2.  Tonsillectomy and the immune system: a long-term follow up comparison between tonsillectomized and non-tonsillectomized children.

Authors:  A Böck; W Popp; K R Herkner
Journal:  Eur Arch Otorhinolaryngol       Date:  1994       Impact factor: 2.503

3.  Effect of tonsillectomy on humeral and cellular immunity: a systematic review of published studies from 2009 to 2019.

Authors:  R G Altwairqi; S M Aljuaid; A S Alqahtani
Journal:  Eur Arch Otorhinolaryngol       Date:  2019-10-29       Impact factor: 2.503

4.  Tonsillectomy and the risk for deep neck infection-a nationwide cohort study.

Authors:  Ying-Piao Wang; Mao-Che Wang; Hung-Ching Lin; Kuo-Sheng Lee; Pesus Chou
Journal:  PLoS One       Date:  2015-04-07       Impact factor: 3.240

  4 in total

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