Literature DB >> 14586110

Synthesis of the racemate and both enantiomers of massoilactone.

Masashi Ishikawa1, Masayasu Amaike, Masamichi Itoh, Yasuhiro Warita, Takeshi Kitahara.   

Abstract

A simple and efficient synthesis of (+/-)-massoilactone (1) as a key substance for the butter and milk flavor was accomplished from n-hexanal in only a few steps. Application of its racemic synthesis enabled natural (R)-(-)- and unnatural (S)-(+)-massoilactone (1a, 1b) to be synthesized by starting from commercially available (R)-(+)-1,2-epoxyheptane (5).

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Year:  2003        PMID: 14586110     DOI: 10.1271/bbb.67.2210

Source DB:  PubMed          Journal:  Biosci Biotechnol Biochem        ISSN: 0916-8451            Impact factor:   2.043


  1 in total

1.  Total Synthesis and Biological Evaluation of Ipomoeassin F and Its Unnatural 11R-Epimer.

Authors:  Guanghui Zong; Eric Barber; Hazim Aljewari; Jianhong Zhou; Zhijian Hu; Yuchun Du; Wei Q Shi
Journal:  J Org Chem       Date:  2015-09-04       Impact factor: 4.354

  1 in total

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