OBJECTIVES: To assess ciprofloxacin resistance among Escherichia coli isolates from bacteraemia patients in England in relation to age, sex and Region. METHODS: Routine susceptibility data for bacteraemia isolates were collected from over 90% of hospitals in England. RESULTS: During 1995-2001, the prevalence of ciprofloxacin resistance trebled, from 2.1% to 6.5%. Isolates from men were more frequently resistant than those from women, possibly because infections in men more often involve nosocomial strains. Resistance was rare (<1.5%) in isolates from patients aged <1 year; among older patients, resistance was unrelated to age in isolates from women, but peaked in the 15-44 age group for men. CONCLUSIONS: The prevalence of ciprofloxacin resistance in E. coli from bacteraemia is strongly associated with sex and, to a lesser extent, age.
OBJECTIVES: To assess ciprofloxacin resistance among Escherichia coli isolates from bacteraemiapatients in England in relation to age, sex and Region. METHODS: Routine susceptibility data for bacteraemia isolates were collected from over 90% of hospitals in England. RESULTS: During 1995-2001, the prevalence of ciprofloxacin resistance trebled, from 2.1% to 6.5%. Isolates from men were more frequently resistant than those from women, possibly because infections in men more often involve nosocomial strains. Resistance was rare (<1.5%) in isolates from patients aged <1 year; among older patients, resistance was unrelated to age in isolates from women, but peaked in the 15-44 age group for men. CONCLUSIONS: The prevalence of ciprofloxacin resistance in E. coli from bacteraemia is strongly associated with sex and, to a lesser extent, age.
Authors: José Miguel Sahuquillo-Arce; María Selva; Hèctor Perpiñán; Miguel Gobernado; Carmen Armero; Antonio López-Quílez; Francisco González; Hermelinda Vanaclocha Journal: Antimicrob Agents Chemother Date: 2011-01-10 Impact factor: 5.191
Authors: Michael Millar; Alex Philpott; Mark Wilks; Angela Whiley; Simon Warwick; Enid Hennessy; Pietro Coen; Stephen Kempley; Fiona Stacey; Kate Costeloe Journal: J Clin Microbiol Date: 2007-11-26 Impact factor: 5.948