Literature DB >> 1458458

Isochromosome 14q and leukemia with dysplastic features.

H W Liu1, K W Lie, L C Chan.   

Abstract

We report a case of chronic myelomonocytic leukemia (CMMoL) with unusual features and an isochromosome 14q as the sole abnormality. A review of the literature suggests that isochromosome 14q (or trisomy 14) is a marker of leukemia with dysplastic features.

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Year:  1992        PMID： 1458458     DOI： 10.1016/0165-4608(92)90333-4

Source DB:  PubMed          Journal:  Cancer Genet Cytogenet        ISSN： 0165-4608


  1 in total

1.  Trisomy 14 as a sole chromosome abnormality is associated with older age, a heterogenous group of myeloid neoplasms with dysplasia, and a wide spectrum of disease progression.

Authors:  Wei Cui; Carlos E Bueso-Ramos; C Cameron Yin; Jianlan Sun; Su Chen; Ramya Muddasani; Gary Lu
Journal:  J Biomed Biotechnol       Date:  2011-01-20
  1 in total

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