Literature DB >> 14583568

Development of radiographic changes of osteoarthritis in the "Chingford knee" reflects progression of disease or non-standardised positioning of the joint rather than incident disease.

S A Mazzuca1, K D Brandt, N C German, K A Buckwalter, K A Lane, B P Katz.   

Abstract

OBJECTIVE: To ascertain the extent to which the "Chingford knee" (that is, contralateral knee of the middle aged, obese, female patient with unilateral knee osteoarthritis (OA)) is a high risk radiographically normal joint as opposed to a knee in which radiographic changes of OA would have been apparent in a more extensive radiographic examination.
METHODS: Subjects were 180 obese women, aged 45-64 years, with unilateral knee OA, based on the standing anteroposterior (AP) view. Subjects underwent a series of radiographic knee examinations: semiflexed AP, supine lateral, and Hughston (patellofemoral (PF)) views. Bony changes of OA were graded by consensus of two readers. Medial tibiofemoral joint space width was measured by digital image analysis. Knee pain was assessed by the WOMAC OA Index after washout of all OA pain drugs.
RESULTS: Despite the absence of evidence of knee OA in the standing AP radiograph, only 32 knees (18%) were radiographically normal in all other views. Ninety four knees (52%) exhibited TF knee OA in the semiflexed AP and/or lateral view. PF OA was seen in 121 knees (67%). Subjects with PF OA reported more severe knee pain than those without PF OA (mean WOMAC scores 9.9 v 8.3, p<0.05).
CONCLUSION: The Chingford knee is not a radiographically normal joint. The high rate of incidence of OA reported previously for this knee ( approximately 50% within two years) may also reflect progression of existing OA or changes in radioanatomical positioning at follow up that showed evidence of stable disease that was present at baseline.

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Year:  2003        PMID: 14583568      PMCID: PMC1754367          DOI: 10.1136/ard.62.11.1061

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN: 0003-4967            Impact factor:   19.103


  23 in total

1.  Effect of alignment of the medial tibial plateau and x-ray beam on apparent progression of osteoarthritis in the standing anteroposterior knee radiograph.

Authors:  S A Mazzuca; K D Brandt; P A Dieppe; M Doherty; B P Katz; K A Lane
Journal:  Arthritis Rheum       Date:  2001-08

2.  Recommendations for the medical management of osteoarthritis of the hip and knee: 2000 update. American College of Rheumatology Subcommittee on Osteoarthritis Guidelines.

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3.  Precision of joint space width measurement in knee osteoarthritis from digital image analysis of high definition macroradiographs.

Authors:  J A Lynch; J C Buckland-Wright; D G Macfarlane
Journal:  Osteoarthritis Cartilage       Date:  1993-10       Impact factor: 6.576

4.  Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association.

Authors:  R Altman; E Asch; D Bloch; G Bole; D Borenstein; K Brandt; W Christy; T D Cooke; R Greenwald; M Hochberg
Journal:  Arthritis Rheum       Date:  1986-08

5.  Validation study of WOMAC: a health status instrument for measuring clinically important patient relevant outcomes to antirheumatic drug therapy in patients with osteoarthritis of the hip or knee.

Authors:  N Bellamy; W W Buchanan; C H Goldsmith; J Campbell; L W Stitt
Journal:  J Rheumatol       Date:  1988-12       Impact factor: 4.666

6.  The association between varus-valgus alignment and patellofemoral osteoarthritis.

Authors:  S Elahi; S Cahue; D T Felson; L Engelman; L Sharma
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7.  Characterisation of size and direction of osteophyte in knee osteoarthritis: a radiographic study.

Authors:  Y Nagaosa; P Lanyon; M Doherty
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8.  Patellofemoral disorders: physical and radiographic evaluation. Part II: Radiographic examination.

Authors:  W G Carson; S L James; R L Larson; K M Singer; W W Winternitz
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9.  Osteoarthritis: MR imaging findings in different stages of disease and correlation with clinical findings.

Authors:  Thomas M Link; Lynne S Steinbach; Srinka Ghosh; Michael Ries; Ying Lu; Nancy Lane; Sharmila Majumdar
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10.  Evaluation of the structure-modifying effects of diacerein in hip osteoarthritis: ECHODIAH, a three-year, placebo-controlled trial. Evaluation of the Chondromodulating Effect of Diacerein in OA of the Hip.

Authors:  M Dougados; M Nguyen; L Berdah; B Maziéres; E Vignon; M Lequesne
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  5 in total

1.  Early stages of osteoarthritis: the search for sensitive predictors.

Authors:  F A Wollheim
Journal:  Ann Rheum Dis       Date:  2003-11       Impact factor: 19.103

2.  Urinary levels of type II collagen C-telopeptide crosslink are unrelated to joint space narrowing in patients with knee osteoarthritis.

Authors:  S A Mazzuca; K D Brandt; D R Eyre; B P Katz; J Askew; K A Lane
Journal:  Ann Rheum Dis       Date:  2005-12-08       Impact factor: 19.103

3.  Risk factors for early radiographic changes of tibiofemoral osteoarthritis.

Authors:  Steven A Mazzuca; Kenneth D Brandt; Barry P Katz; Yan Ding; Kathleen A Lane; Kenneth A Buckwalter
Journal:  Ann Rheum Dis       Date:  2006-08-22       Impact factor: 19.103

4.  Premorbid knee osteoarthritis is not characterised by diffuse thinness: the Framingham Osteoarthritis Study.

Authors:  D J Hunter; J B Niu; Y Zhang; M LaValley; C E McLennan; M Hudelmaier; F Eckstein; D T Felson
Journal:  Ann Rheum Dis       Date:  2008-01-24       Impact factor: 19.103

5.  Is knee osteoarthritis a symmetrical disease? Analysis of a 12 year prospective cohort study.

Authors:  Andrew J Metcalfe; Maria L E Andersson; Rhian Goodfellow; Carina A Thorstensson
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  5 in total

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