Literature DB >> 14583263

Simultaneous in vitro assay of the first four enzymes in the fungal aspartate pathway identifies a new class of aspartate kinase inhibitor.

David C Bareich1, Ishac Nazi, Gerard D Wright.   

Abstract

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Year:  2003        PMID： 14583263     DOI： 10.1016/j.chembiol.2003.09.016

Source DB:  PubMed          Journal:  Chem Biol        ISSN： 1074-5521


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  6 in total

1.  High-throughput screening identifies novel inhibitors of the acetyltransferase activity of Escherichia coli GlmU.

Authors:  Mark P Pereira; Jan E Blanchard; Cecilia Murphy; Steven L Roderick; Eric D Brown
Journal:  Antimicrob Agents Chemother       Date:  2009-04-06       Impact factor: 5.191

2.  Targeting the Homoserine Dehydrogenase of Paracoccidioides Species for Treatment of Systemic Fungal Infections.

Authors:  Mariane C Bagatin; Arethusa L Pimentel; Débora C Biavatti; Ernani A Basso; Erika S Kioshima; Flavio A V Seixas; Gisele de F Gauze
Journal:  Antimicrob Agents Chemother       Date:  2017-08-24       Impact factor: 5.191

3.  Role of homoserine transacetylase as a new target for antifungal agents.

Authors:  Ishac Nazi; Adam Scott; Anita Sham; Laura Rossi; Peter R Williamson; James W Kronstad; Gerard D Wright
Journal:  Antimicrob Agents Chemother       Date:  2007-03-12       Impact factor: 5.191

4.  Threonine-insensitive homoserine dehydrogenase from soybean: genomic organization, kinetic mechanism, and in vivo activity.

Authors:  Amy C Schroeder; Chuanmei Zhu; Srinivasa Rao Yanamadala; Rebecca E Cahoon; Kiani A J Arkus; Leia Wachsstock; Jeremy Bleeke; Hari B Krishnan; Joseph M Jez
Journal:  J Biol Chem       Date:  2009-11-06       Impact factor: 5.157

Review 5.  Inhibitors of amino acids biosynthesis as antifungal agents.

Authors:  Kamila Jastrzębowska; Iwona Gabriel
Journal:  Amino Acids       Date:  2014-11-20       Impact factor: 3.520

6.  Exploring the molecular basis for selective binding of homoserine dehydrogenase from Mycobacterium leprae TN toward inhibitors: a virtual screening study.

Authors:  Dongling Zhan; Dongmei Wang; Weihong Min; Weiwei Han
Journal:  Int J Mol Sci       Date:  2014-01-24       Impact factor: 5.923
  6 in total

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