| Literature DB >> 14583013 |
Subramanian Karur1, S R S Saibabu Kotti, Xin Xu, John F Cannon, Allan Headley, Guigen Li.
Abstract
The first multiple-site activation of alkynes with amine/halogen functionalities has been established. The reaction was performed by treating alkyne with N,N-dichlorobenzenesulfonamide at 80 degrees C in the presence of palladium acetate catalyst. A new mechanism was proposed which involves the novel formation of beta-halovinyl palladium and pi-allylpalladium species. Excellent regio- and stereoselectivities were achieved with the absolute structure determined by X-ray structural analysis.Entities:
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Year: 2003 PMID： 14583013 DOI： 10.1021/ja0304188
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419