| Literature DB >> 14582645 |
Tomoyoshi Soga1, Yoshiaki Ohashi, Yuki Ueno, Hisako Naraoka, Masaru Tomita, Takaaki Nishioka.
Abstract
A new approach for the comprehensive and quantitative analysis of charged metabolites by capillary electrophoresis mass spectrometry (CE-MS) is proposed. Metabolites are first separated by CE based on charge and size and then selectively detected using MS by monitoring over a large range of m/z values. This method enabled the determination of 352 metabolic standards and its utility was demonstrated in the analysis of 1692 metabolites from Bacillus subtilis extracts, revealing significant changes in metabolites during B. subtilis sporulation.Entities:
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Year: 2003 PMID: 14582645 DOI: 10.1021/pr034020m
Source DB: PubMed Journal: J Proteome Res ISSN: 1535-3893 Impact factor: 4.466