Literature DB >> 14581683

Brain metabolic differences between sporadic and familial Alzheimer's disease.

L Mosconi1, S Sorbi, B Nacmias, M T R De Cristofaro, M Fayyaz, E Cellini, S Bagnoli, L Bracco, K Herholz, A Pupi.   

Abstract

This FDG-PET study with SPM99 compared 46 patients with sporadic Alzheimer disease (SAD) to 40 patients with familial AD (FAD) and to 35 matched controls. AD groups had equivalent metabolic (METglu) reductions in several cortical and limbic areas with respect to the controls. Patients with FAD showed decreased METglu in the posterior cingulate, parahippocampal, and occipital cortex as compared to the patients with SAD (p < 0.001). Genetic factors lead to phenotypic differences in AD.

Entities:  

Mesh：

Substances：

Year:  2003        PMID： 14581683     DOI： 10.1212/01.wnl.0000086816.30011.75

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  10 in total

Review 1.  Brain fuel metabolism, aging, and Alzheimer's disease.

Authors:  Stephen Cunnane; Scott Nugent; Maggie Roy; Alexandre Courchesne-Loyer; Etienne Croteau; Sébastien Tremblay; Alex Castellano; Fabien Pifferi; Christian Bocti; Nancy Paquet; Hadi Begdouri; M'hamed Bentourkia; Eric Turcotte; Michèle Allard; Pascale Barberger-Gateau; Tamas Fulop; Stanley I Rapoport
Journal:  Nutrition       Date:  2010-10-29       Impact factor: 4.008

2.  Comparing fludeoxyglucose F18-PET assessment of regional cerebral glucose metabolism and [11C]dihydrotetrabenazine-PET in evaluation of early dementia and mild cognitive impairment.

Authors:  Roger L Albin; Robert A Koeppe; James F Burke; Bruno Giordani; Michael R Kilbourn; Sid Gilman; Kirk A Frey
Journal:  Arch Neurol       Date:  2010-04

3.  Metabolic interaction between ApoE genotype and onset age in Alzheimer's disease: implications for brain reserve.

Authors:  L Mosconi; K Herholz; I Prohovnik; B Nacmias; M T R De Cristofaro; M Fayyaz; L Bracco; S Sorbi; A Pupi
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-01       Impact factor: 10.154

Review 4.  Toward the validation of functional neuroimaging as a potential biomarker for Alzheimer's disease: implications for drug development.

Authors:  Alberto Pupi; Lisa Mosconi; Flavio M Nobili; Sandro Sorbi
Journal:  Mol Imaging Biol       Date:  2005 Jan-Feb       Impact factor: 3.488

5.  Effects of exercise training on brain metabolism and cognitive functioning in sleep apnea.

Authors:  Linda M Ueno-Pardi; Fabio L Souza-Duran; Larissa Matheus; Amanda G Rodrigues; Eline R F Barbosa; Paulo J Cunha; Camila G Carneiro; Naomi A Costa; Carla R Ono; Carlos A Buchpiguel; Carlos E Negrão; Geraldo Lorenzi-Filho; Geraldo Busatto-Filho
Journal:  Sci Rep       Date:  2022-06-08       Impact factor: 4.996

Review 6.  Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD.

Authors:  Lisa Mosconi
Journal:  Eur J Nucl Med Mol Imaging       Date:  2005-04       Impact factor: 9.236

Review 7.  Diagnostic utility of 18F-Fluorodeoxyglucose positron emission tomography (FDG-PET) in asymptomatic subjects at increased risk for Alzheimer's disease.

Authors:  Alexander Drzezga; Daniele Altomare; Cristina Festari; Javier Arbizu; Stefania Orini; Karl Herholz; Peter Nestor; Federica Agosta; Femke Bouwman; Flavio Nobili; Zuzana Walker; Giovanni Battista Frisoni; Marina Boccardi
Journal:  Eur J Nucl Med Mol Imaging       Date:  2018-05-13       Impact factor: 9.236

8.  Differences in extracellular matrix production and basic fibroblast growth factor response in skin fibroblasts from sporadic and familial Alzheimer's disease.

Authors:  Catia Bellucci; Cinzia Lilli; Tiziano Baroni; Lucilla Parnetti; Sandro Sorbi; Carla Emiliani; Eleonora Lumare; Paolo Calabresi; Stefania Balloni; Maria Bodo
Journal:  Mol Med       Date:  2007 Sep-Oct       Impact factor: 6.354

9.  Neuronal and astrocytic metabolism in a transgenic rat model of Alzheimer's disease.

Authors:  Linn Hege Nilsen; Menno P Witter; Ursula Sonnewald
Journal:  J Cereb Blood Flow Metab       Date:  2014-03-05       Impact factor: 6.200

Review 10.  Questions concerning the role of amyloid-β in the definition, aetiology and diagnosis of Alzheimer's disease.

Authors:  Gary P Morris; Ian A Clark; Bryce Vissel
Journal:  Acta Neuropathol       Date:  2018-10-22       Impact factor: 17.088
  10 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.