| Literature DB >> 14581577 |
Andreas N Madsen1, Anneline Nansen, Jan P Christensen, Allan R Thomsen.
Abstract
The immune response to lymphocytic choriomeningitis virus in mice lacking macrophage inflammatory protein-1alpha (MIP-1alpha) was evaluated. Generation of virus-specific effector T cells is unimpaired in MIP-1alpha-deficient mice. Furthermore, MIP-1alpha is not required for T-cell-mediated virus control or virus-induced T-cell-dependent inflammation. Thus, MIP-1alpha is not mandatory for T-cell-mediated antiviral immunity.Entities:
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Year: 2003 PMID: 14581577 PMCID: PMC254281 DOI: 10.1128/jvi.77.22.12378-12384.2003
Source DB: PubMed Journal: J Virol ISSN: 0022-538X Impact factor: 5.103