Literature DB >> 14581252

Restless legs syndrome symptoms in primary care: a prevalence study.

Deborah A Nichols1, Richard P Allen, John H Grauke, John B Brown, Matthew L Rice, Pamela R Hyde, William C Dement, Clete A Kushida.   

Abstract

BACKGROUND: There are relatively few studies on the prevalence of restless legs syndrome (RLS) in the general population, even fewer that used diagnostic questions covering all 4 essential diagnostic criteria defining the RLS symptom complex, and none that have reported on the 2 RLS phenotypes for patients seen by family physicians.
METHODS: To determine the prevalence of the symptom complex, diagnostic for RLS in a primary care patient population, a prospective population-based single-center study was performed. Every adult patient presenting for care in a small rural primary care practice with mostly white patients was surveyed for a 1-year period using a validated RLS diagnostic questionnaire.
RESULTS: A total of 2099 patients completed the questionnaire. Analysis revealed that 24.0% of these patients were positive for all 4 of the essential symptoms used to make the diagnosis of RLS and 15.3% reported these symptoms at least weekly. In addition, the RLS symptom complex was reported significantly more often by women than men and, as a whole, patients reporting the RLS symptoms were significantly older than patients without symptoms. The prevalence of symptoms increased with age until about 60 years and then showed a steady decrease thereafter. Further, early-onset RLS was significantly more common in women than men.
CONCLUSIONS: A high prevalence of RLS symptoms was observed in this primary care population. This finding supports the need for heightened awareness in both the medical community and general population regarding this disorder, which can often be effectively treated within the primary care practice.

Entities:  

Mesh:

Year:  2003        PMID: 14581252     DOI: 10.1001/archinte.163.19.2323

Source DB:  PubMed          Journal:  Arch Intern Med        ISSN: 0003-9926


  40 in total

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Review 4.  Prevalence of restless legs syndrome in North American and Western European populations: a systematic review.

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Review 5.  An update on the pathophysiology and genetics of restless legs syndrome.

Authors:  Lynn Marie Trotti; Srinivas Bhadriraju; David B Rye
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6.  A randomized, double-blind, placebo-controlled, crossover study of XP13512/GSK1838262 in the treatment of patients with primary restless legs syndrome.

Authors:  Clete A Kushida; Arthur S Walters; Philip Becker; Stephen G Thein; A Thomas Perkins; Thomas Roth; Daniel Canafax; Ronald W Barrett
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7.  No evidence for cognitive dysfunction or depression in patients with mild restless legs syndrome.

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8.  A Collaborative Paradigm for Improving Management of Sleep Disorders in Primary Care: A Randomized Clinical Trial.

Authors:  Jack D Edinger; Janet Grubber; Christi Ulmer; Jennifer Zervakis; Maren Olsen
Journal:  Sleep       Date:  2016-01-01       Impact factor: 5.849

9.  Diurnal cycle influences peripheral and brain iron levels in mice.

Authors:  Erica L Unger; Christopher J Earley; John L Beard
Journal:  J Appl Physiol (1985)       Date:  2008-11-06

Review 10.  Sleep disorders and quality of life in renal transplant recipients.

Authors:  Miklos Zsolt Molnar; Marta Novak; Istvan Mucsi
Journal:  Int Urol Nephrol       Date:  2009-01-31       Impact factor: 2.370

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