Literature DB >> 14581097

The experience of loss and anticipation of distress in colorectal cancer patients undergoing genetic testing.

Mary Jane Esplen1, Cristine Urquhart, Kate Butler, Steven Gallinger, Melyssa Aronson, Jiahui Wong.   

Abstract

OBJECTIVE: The purpose of this paper is to describe pretest psychological functioning in a sample of colorectal cancer (CRC) patients undergoing genetic testing. We also explored the relationship among demographic, medical, family history and loss variables and current pretest distress, and those related to anticipated posttest distress.
METHODS: This paper reports pretest findings from a prospective, longitudinal psychosocial survey. Data are presented on 220 CRC patients at pretest.
RESULTS: We found a subgroup of CRC patients that are currently distressed and anticipate becoming depressed if they receive a positive genetic test result. There were significant associations among pretest distress, family history of CRC and loss related to CRC and anticipation of becoming depressed at posttest.
CONCLUSIONS: The findings suggest that a subgroup of CRC patient's experience or anticipate distress that may warrant attention. Family history of CRC and losses related to CRC may be important indicators of posttest adjustment.

Entities:  

Mesh:

Year:  2003        PMID: 14581097     DOI: 10.1016/s0022-3999(03)00511-7

Source DB:  PubMed          Journal:  J Psychosom Res        ISSN: 0022-3999            Impact factor:   3.006


  9 in total

1.  Limited impact on self-concept in individuals with Lynch syndrome; results from a national cohort study.

Authors:  Helle Vendel Petersen; Mary Jane Esplen; Steen Ladelund; Inge Bernstein; Lone Sunde; Christina Carlsson; Mef Nilbert
Journal:  Fam Cancer       Date:  2011-12       Impact factor: 2.375

Review 2.  100 years Lynch syndrome: what have we learned about psychosocial issues?

Authors:  Eveline M A Bleiker; Mary Jane Esplen; Bettina Meiser; Helle Vendel Petersen; Andrea Farkas Patenaude
Journal:  Fam Cancer       Date:  2013-06       Impact factor: 2.375

3.  Living with hereditary non-polyposis colorectal cancer; experiences from and impact of genetic testing.

Authors:  C Carlsson; M Nilbert
Journal:  J Genet Couns       Date:  2007-08-18       Impact factor: 2.537

4.  Waiting and "weighted down": the challenge of anticipatory loss for individuals and families with Li-Fraumeni Syndrome.

Authors:  Allison Werner-Lin; Jennifer L Young; Catherine Wilsnack; Shana L Merrill; Victoria Groner; Mark H Greene; Payal P Khincha
Journal:  Fam Cancer       Date:  2020-07       Impact factor: 2.375

5.  The influence of cancer-related distress and sense of coherence on anxiety and depression in patients with hereditary cancer: a study of patients' sense of coherence 6 months after genetic counseling.

Authors:  Elen Siglen; Cathrine Bjorvatn; Lars Fredrik Engebretsen; Gunilla Berglund; Gerd Karin Natvig
Journal:  J Genet Couns       Date:  2007-08-12       Impact factor: 2.537

6.  The impact of familial environment on depression scores after genetic testing for cancer susceptibility.

Authors:  S Ashida; D W Hadley; B K Vaughn; N R Kuhn; J F Jenkins; L M Koehly
Journal:  Clin Genet       Date:  2008-11-17       Impact factor: 4.438

7.  Development and preliminary testing of the psychosocial adjustment to hereditary diseases scale.

Authors:  Kathy E Watkins; Christine Y Way; Deborah M Gregory; Holly M LeDrew; Valerie C Ludlow; Mary Jane Esplen; Jeffrey J Dowden; Janet E Cox; G William N Fitzgerald; Patrick S Parfrey
Journal:  BMC Psychol       Date:  2013-04-30

Review 8.  Genetic testing for Lynch syndrome in the first year of colorectal cancer: a review of the psychological impact.

Authors:  Karin M Landsbergen; Judith B Prins; Han G Brunner; Floris W Kraaimaat; Nicoline Hoogerbrugge
Journal:  Fam Cancer       Date:  2009-03-28       Impact factor: 2.375

9.  Development and validation of a brief screening instrument for psychosocial risk associated with genetic testing: a pan-Canadian cohort study.

Authors:  Mary Jane Esplen; Mario Cappelli; Jiahui Wong; Joan L Bottorff; Jon Hunter; June Carroll; Michel Dorval; Brenda Wilson; Judith Allanson; Kara Semotiuk; Melyssa Aronson; Louise Bordeleau; Nicole Charlemagne; Wendy Meschino
Journal:  BMJ Open       Date:  2013-03-13       Impact factor: 2.692

  9 in total

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