Literature DB >> 14577505

Wegener's granulomatosis diagnosed by testicular biopsy.

Mahendra Agraharkar1, Sumita Gokhale, Rajiv Gupta.   

Abstract

Urogenital involvement, other than the kidneys, is extremely rare in Wegener's granulomatosis (WG) and occurs in less than 1% of the cases. When encountered it is confined to prostate, bladder, urethra, cervix, and vagina. Granulomatous infiltration of the testis from WG has not been cited in the medical literature. We report a case of WG in a Hispanic male who presented with sensorineural hearing loss and hemoptysis. He had a pulmonary lesion and a painless right testicular mass, which was found to have necrotizing granulomas on excisional biopsy. This may be the first reported case of WG diagnosed by testicular biopsy as testicular involvement is rare in WG. We believe that the actual incidence of testicular involvement in WG may be higher as genital examination may be ignored during routine physical examinations.

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Year:  2002        PMID: 14577505     DOI: 10.1023/a:1025642217482

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  16 in total

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Authors:  C A Langford; G S Hoffman
Journal:  Thorax       Date:  1999-07       Impact factor: 9.139

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Journal:  J Urol       Date:  1999-03       Impact factor: 7.450

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Journal:  Cleve Clin J Med       Date:  1998-03       Impact factor: 2.321

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Journal:  Postgrad Med J       Date:  1987-01       Impact factor: 2.401

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Journal:  Lancet       Date:  1995-10-07       Impact factor: 79.321

7.  The epidemiology of Wegener's granulomatosis. Estimates of the five-year period prevalence, annual mortality, and geographic disease distribution from population-based data sources.

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Journal:  Arthritis Rheum       Date:  1996-01

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Authors:  V J Bray; J A Hasbargen
Journal:  Am J Kidney Dis       Date:  1991-05       Impact factor: 8.860

9.  Anti-proteinase 3 antibodies, their characterization and disease associations.

Authors:  J G Jennings; L Chang; J A Savige
Journal:  Clin Exp Immunol       Date:  1994-02       Impact factor: 4.330

10.  Urogenital manifestations of Wegener granulomatosis.

Authors:  D L Huong; T Papo; J C Piette; B Wechsler; O Bletry; F Richard; J C Valcke; P Godeau
Journal:  Medicine (Baltimore)       Date:  1995-05       Impact factor: 1.889

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  1 in total

1.  An Unusual Presentation of Limited Granulomatosis with Polyangiitis Involving Vagina and Urethra.

Authors:  Sandra Soro Marín; Enrique Júdez Navarro; Manuela Sianes Fernández; Ginés Sánchez Nievas; Juan Gabriel Lorenzo Romero
Journal:  Case Rep Rheumatol       Date:  2017-03-13
  1 in total

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