Literature DB >> 14577484

Extracorporeal shock wave lithotripsy for cystine urolithiasis in children: outcome and complications.

Andjelka Slavković1, Miladin Radovanović, Zlatko Sirić, Marina Vlajković, Vladisav Stefanović.   

Abstract

The Siemens Lithostar Litotriptor was used to treat 6 children with cystine nephrolithiasis, previously treated by open surgery. Five children had renal calculi (3 multiple caliceal, 2 pelvis) and one had ureteral calculus. Stone size ranged from 0.2-2.5 cm in diameter, and stone burden was from 0.24 to 10.81 cm3 per kidney. From one to 4 ESWL sessions per unit were applied, with a total of 1,800 to 12,000 shock waves. The stone free rate at 3 months was 50%. A complete elimination was obtained with cystine stones in renal pelvis and ureter, however, up to 4 ESWL treatments failed in caliceal stones. Rather location of cystine calculi than previous surgery was associated with ESWL success rate. Two patients with positive urine cultures were successfully treated with appropriate antibiotics before ESWL was attempted. Perirenal hematoma was major complication demonstrated by radionuclide scintigraphy in one patient, and resolved spontaneously by 3 months. In the combined treatment of cystine urolithiasis in children ESWL, as auxillary procedure, was safe and effective in pelvis stone but failed in caliceal stones. Medical dissolution for retained fragments was found effective.

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Year:  2002        PMID: 14577484     DOI: 10.1023/a:1025694230131

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  13 in total

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Review 1.  Cystinuria: genetic aspects, mouse models, and a new approach to therapy.

Authors:  Amrik Sahota; Jay A Tischfield; David S Goldfarb; Michael D Ward; Longqin Hu
Journal:  Urolithiasis       Date:  2018-12-04       Impact factor: 3.436

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Journal:  Eur J Pediatr       Date:  2010-10-06       Impact factor: 3.183

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Authors:  A Slavkovic; M Radovanovic; M Vlajkovic; D Novakovic; N Djordjevic; V Stefanovic
Journal:  Urol Res       Date:  2006-07-26

4.  Can cystinuria decrease the effectiveness of RIRS with high-power ho:yag laser in children? Outcomes from a tertiary endourology referral center.

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Journal:  Urolithiasis       Date:  2022-01-27       Impact factor: 3.436

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Authors:  Marc C Smaldone; Bishoy A Gayed; Michael C Ost
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  7 in total

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